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D-dimer level for predicting the in-hospital mortality in liver cirrhosis: A retrospective study

Authors :
Jing Li
Xiaolin Sun
Xingshun Qi
Yun Li
Hongyu Li
Ying Peng
Han Deng
Junna Dai
Xu Liu
Xiaozhong Guo
Source :
Experimental and Therapeutic Medicine. 13:285-289
Publication Year :
2016
Publisher :
Spandidos Publications, 2016.

Abstract

The present study aimed to examine the correlation of D-dimer levels with the Child-Pugh and MELD scores, as well as to determine the predictive ability of D-dimer level for the in-hospital mortality of liver cirrhosis patients. All cirrhotic patients who were consecutively admitted to our hospital between January 2011 and June 2014, and underwent D-dimer tests on admission were retrospectively analyzed. Pearson's χ2 tests were employed to evaluate the correlations of D-dimer levels with Child-Pugh and MELD scores. In addition, receiver operating curve (ROC) analysis was employed to evaluate the specificity and sensitivity of D-dimer levels for predicting the in-hospital mortality. In total, 703 cirrhotic patients were included in the study, with an in-hospital mortality of 5.4% (38/703). The D-dimer levels were correlated with Child-Pugh (correlation coefficient, 0.219; P15 group compared with the MELD score

Details

ISSN :
17921015 and 17920981
Volume :
13
Database :
OpenAIRE
Journal :
Experimental and Therapeutic Medicine
Accession number :
edsair.doi.dedup.....b960533c83420924cbd7a6c9a56f44ae