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Prognostic value of global left atrial peak strain in patients with acute ischemic stroke and no evidence of atrial fibrillation
- Source :
- The International Journal of Cardiovascular Imaging. 35:603-613
- Publication Year :
- 2018
- Publisher :
- Springer Science and Business Media LLC, 2018.
-
Abstract
- Prognostic stratification of acute ischemic stroke (AIS) patients without atrial fibrillation (AF) remains a challenge. Two-dimensional speckle tracking echocardiography (2D-STE) has recently been introduced for dynamic evaluation of left atrial function. However only few data are actually available regarding the application of 2D-STE in AIS patients. The aim of our study was to assess the prognostic role of global left atrial peak strain (GLAPS), measured by 2D-STE, in AIS patients without AF history. Eighty-five AIS patients (mean age 74.1 ± 12.1 years, 49 males) with normal sinus rhythm on ECG and without AF history were enrolled in the prospective study. All patients underwent a complete echocardiographic study with 2D-STE. At 1 year follow-up, we evaluated the occurrence of a composite endpoint of all-cause mortality plus cardiovascular re-hospitalizations. GLAPS was markedly reduced in AIS patients (15.71 ± 4.70%), without any statistically significant difference between the stroke subtypes. At 1-year follow-up, 14 deaths and 17 hospital readmissions were detected in AIS subjects. On a multivariate Cox model, variables independently associated with the occurrence of the composite endpoint were the “Rankin in” Scale (HR 1.69, p = 0.001), GFR (HR 0.98, p = 0.03) and the GLAPS value (HR 0.78, p
- Subjects :
- Male
medicine.medical_specialty
Speckle tracking echocardiography
030204 cardiovascular system & hematology
Patient Readmission
Brain Ischemia
03 medical and health sciences
0302 clinical medicine
Predictive Value of Tests
Risk Factors
Left atrial
Internal medicine
medicine
Humans
Radiology, Nuclear Medicine and imaging
Heart Atria
Prospective Studies
Prospective cohort study
Stroke
Acute ischemic stroke
Cardiac imaging
Aged
Aged, 80 and over
business.industry
Proportional hazards model
Atrial fibrillation
Middle Aged
Prognosis
medicine.disease
Echocardiography, Doppler
Cardiology
Atrial Function, Left
Female
Cardiology and Cardiovascular Medicine
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 15730743 and 15695794
- Volume :
- 35
- Database :
- OpenAIRE
- Journal :
- The International Journal of Cardiovascular Imaging
- Accession number :
- edsair.doi.dedup.....b964b219bce58dfdc2f38f92b1e54401
- Full Text :
- https://doi.org/10.1007/s10554-018-1485-z