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Prognostic value of global left atrial peak strain in patients with acute ischemic stroke and no evidence of atrial fibrillation

Authors :
Gian Luigi Nicolosi
Elisabetta Rigamonti
Pietro Bassi
Andrea Sonaglioni
Massimo Baravelli
Michele Lombardo
Claudio Anzà
Elena Tagliabue
Antonio Vincenti
Source :
The International Journal of Cardiovascular Imaging. 35:603-613
Publication Year :
2018
Publisher :
Springer Science and Business Media LLC, 2018.

Abstract

Prognostic stratification of acute ischemic stroke (AIS) patients without atrial fibrillation (AF) remains a challenge. Two-dimensional speckle tracking echocardiography (2D-STE) has recently been introduced for dynamic evaluation of left atrial function. However only few data are actually available regarding the application of 2D-STE in AIS patients. The aim of our study was to assess the prognostic role of global left atrial peak strain (GLAPS), measured by 2D-STE, in AIS patients without AF history. Eighty-five AIS patients (mean age 74.1 ± 12.1 years, 49 males) with normal sinus rhythm on ECG and without AF history were enrolled in the prospective study. All patients underwent a complete echocardiographic study with 2D-STE. At 1 year follow-up, we evaluated the occurrence of a composite endpoint of all-cause mortality plus cardiovascular re-hospitalizations. GLAPS was markedly reduced in AIS patients (15.71 ± 4.70%), without any statistically significant difference between the stroke subtypes. At 1-year follow-up, 14 deaths and 17 hospital readmissions were detected in AIS subjects. On a multivariate Cox model, variables independently associated with the occurrence of the composite endpoint were the “Rankin in” Scale (HR 1.69, p = 0.001), GFR (HR 0.98, p = 0.03) and the GLAPS value (HR 0.78, p

Details

ISSN :
15730743 and 15695794
Volume :
35
Database :
OpenAIRE
Journal :
The International Journal of Cardiovascular Imaging
Accession number :
edsair.doi.dedup.....b964b219bce58dfdc2f38f92b1e54401
Full Text :
https://doi.org/10.1007/s10554-018-1485-z