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Supplementary Figure 2 from Vaccination with mRNA-Electroporated Dendritic Cells Induces Robust Tumor Antigen-Specific CD4+ and CD8+ T Cells Responses in Stage III and IV Melanoma Patients

Authors :
Gosse J. Adema
Cornelis J. A. Punt
Carl G. Figdor
I. Jolanda M. de Vries
Kris Thielemans
Roel Mus
Danita H. Schuurhuis
Tjitske Duiveman-de Boer
Joannes F. M. Jacobs
Willeke A. M. Blokx
Michelle M. van Rossum
Johannes H. W. de Wilt
Alexandra J. Croockewit
W. Joost Lesterhuis
Kalijn Bol
Gerty Schreibelt
Erik H. J. G. Aarntzen
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

PDF file, 1359K, Vaccine characteristics of first cycle of all patients. (A) Expression of HLA-ABC, HLA-DR/DP, HLA-DQ, CD80, CD86, CD83, and CCR7 was analyzed by flow cytometry. (B) Tumor antigen expression by DCs 2-4 hrs after electroporation with mRNA encoding gp100 and tyrosinase. Data are shown as percentage of positive DCs used for the first vaccination. The graphs represent mean � SD of all patients.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....b9972bd46e8e67d96947535baab7380c