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Estimating dyskinesia severity in Parkinson’s disease by using a waist-worn sensor: concurrent validity study
- Source :
- Scientific Reports, Vol 9, Iss 1, Pp 1-7 (2019), Scientific Reports, UPCommons. Portal del coneixement obert de la UPC, Universitat Politècnica de Catalunya (UPC)
- Publication Year :
- 2019
- Publisher :
- Nature Publishing Group, 2019.
-
Abstract
- Our research team previously developed an accelerometry-based device, which can be worn on the waist during daily life activities and detects the occurrence of dyskinesia in patients with Parkinson’s disease. The goal of this study was to analyze the magnitude of correlation between the numeric output of the device algorithm and the results of the Unified Dyskinesia Rating Scale (UDysRS), administered by a physician. In this study, 13 Parkinson’s patients, who were symptomatic with dyskinesias, were monitored with the device at home, for an average period of 30 minutes, while performing normal daily life activities. Each patient’s activity was simultaneously video-recorded. A physician was in charge of reviewing the recorded videos and determining the severity of dyskinesia through the UDysRS for every patient. The sensor device yielded only one value for dyskinesia severity, which was calculated by averaging the recorded device readings. Correlation between the results of physician’s assessment and the sensor output was analyzed with the Spearman’s correlation coefficient. The correlation coefficient between the sensor output and UDysRS result was 0.70 (CI 95%: 0.33–0.88; p = 0.01). Since the sensor was located on the waist, the correlation between the sensor output and the results of the trunk and legs scale sub-items was calculated: 0.91 (CI 95% 0.76–0.97: p
- Subjects :
- 0301 basic medicine
Male
medicine.medical_specialty
Waist
Parkinson's disease
Correlation coefficient
Ciències de la salut::Medicina [Àrees temàtiques de la UPC]
Concurrent validity
Video Recording
lcsh:Medicine
Learning algorithms
Article
Correlation
Cohort Studies
03 medical and health sciences
Wearable Electronic Devices
0302 clinical medicine
Physical medicine and rehabilitation
Rating scale
Accelerometry
medicine
Humans
Parkinson, Malaltia de
lcsh:Science
Aged
Monitoring, Physiologic
Multidisciplinary
Dyskinesias
business.industry
lcsh:R
Parkinson Disease
Middle Aged
medicine.disease
Trunk
Drug regulation
030104 developmental biology
Dyskinesia
Drug delivery
Parkinson’s disease
Female
lcsh:Q
medicine.symptom
business
030217 neurology & neurosurgery
Algorithms
Subjects
Details
- Language :
- English
- ISSN :
- 20452322
- Volume :
- 9
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Scientific Reports
- Accession number :
- edsair.doi.dedup.....ba1160fb70da828ba357cdc30b91cc0a
- Full Text :
- https://doi.org/10.1038/s41598-019-49798-3