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Anthracycline‑induced cardiotoxicity in the chemotherapy treatment of breast cancer: Preventive strategies and treatment (Review)
- Source :
- Molecular and Clinical Oncology
- Publication Year :
- 2019
- Publisher :
- Spandidos Publications, 2019.
-
Abstract
- Anthracyclines are highly effective chemotherapeutic agents, used for a wide variety of malignancies. Cardiotoxicity is a well-recognized side effect of anthracycline therapy that limits the total amount of drug administered and can cause heart failure in some patients. Most experimental data support oxidative stress as the etiology of anthracycline-induced cardiotoxicity. The objective of this paper was to provide a review of the clinical classification, risk factors, monitoring and prevention of anthracycline-induced cardiotoxicity in patients with breast cancer.
- Subjects :
- Drug
Oncology
Cancer Research
medicine.medical_specialty
Side effect
Anthracycline
media_common.quotation_subject
medicine.medical_treatment
cardiotoxicity
Review
doxorubicin
03 medical and health sciences
breast cancer
0302 clinical medicine
Breast cancer
prevention
Internal medicine
risk factors
Medicine
Doxorubicin
media_common
anthracyclines
Cardiotoxicity
Chemotherapy
treatment
business.industry
Cancer
medicine.disease
030220 oncology & carcinogenesis
030211 gastroenterology & hepatology
business
medicine.drug
Subjects
Details
- ISSN :
- 20499469 and 20499450
- Database :
- OpenAIRE
- Journal :
- Molecular and Clinical Oncology
- Accession number :
- edsair.doi.dedup.....ba6c270fc29c4abd689737f0763daad4