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Transmissibility of SARS-CoV-2 Variants as a Secondary Attack in Thai Households: a Retrospective Study
- Source :
- IJID Regions
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- Objective Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spreads through person-to-person contact via small droplet particles, especially in poorly ventilated indoor settings such as households, estimating at 16.6% of secondary attack rate. This study aimed to explore the secondary attack rate in Thai households during the new SARS-CoV-2 variant outbreak. Methods We obtained a retrospective study of exposed members in households among 30 sets of patients with reverse transcriptase-polymerase chain reaction (RT-PCR) confirmed SARS-CoV-2 infection (index cases) at Chulabhorn Hospital, Bangkok, Thailand, from May 1 to June 30, 2021. Characteristic of index cases and households were extracted from medical records and analyzed. Results The 30 index cases were associated with 157 exposed household close contacts. Seventy-six were RT-PCR confirmed SARS-CoV-2 infections within 14 days after being exposed from an index case, with a secondary attack rate of 48%. However, there was no difference between secondary attack rates among the age of contact, household size, or SARS-CoV-2 variants. Conclusion Our data show high transmissibility of SARS-CoV-2, which was notably exaggerated compared to previous studies. Therefore, developing preventive strategies such as post-exposure prophylaxis (PEP) in close contact with SARS-CoV-2 infection would be a novel supplement to the current standard of care.
- Subjects :
- Variants of concern
SARS-CoV-2
business.industry
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Medical record
Small droplet
COVID-19
Outbreak
Retrospective cohort study
Article
Secondary attack
Transmissibility (vibration)
Household transmission
Environmental health
Medicine
Transmission risks and rates
Thai
business
Index case
Subjects
Details
- ISSN :
- 27727076
- Volume :
- 1
- Database :
- OpenAIRE
- Journal :
- IJID Regions
- Accession number :
- edsair.doi.dedup.....bb039b28f3f0d81a8f5eff80376d7f1d