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Temporal effects of infection control practices and the use of antibiotics on the incidence of MRSA
- Source :
- J Hosp Infect, J Hosp Infect, 2012, 82 (3), pp.164-9. ⟨10.1016/j.jhin.2012.07.013⟩, J Hosp Infect, 2012, 82 (3), pp.164-9. 〈10.1016/j.jhin.2012.07.013〉
- Publication Year :
- 2012
- Publisher :
- HAL CCSD, 2012.
-
Abstract
- International audience; BACKGROUND: Meticillin-resistant Staphylococcus aureus (MRSA) has spread throughout the world and has become highly endemic worldwide. The need for implementing MRSA control strategies is no longer a matter of debate. AIM: To determine the temporal association between various infection control practices, the use of antibiotics and the incidence of MRSA in a 1200-bed French university hospital. METHODS: A multi-variate time-series analysis, based on monthly data from a nine-year period (January 2000-December 2008), was performed in a 1200-bed French university hospital to determine the temporal association between different variables and the incidence of MRSA. MRSA colonization pressure, infection control practices and use of antibiotics were considered in the analysis. FINDINGS: Time-series analysis showed a positive significant relationship between the incidence of hospital-acquired MRSA (HA-MRSA) and MRSA colonization pressure, the use of antibiotics (fluoroquinolones, macrolides and aminoglycosides) and the use of gloves. Conversely, a global negative correlation was observed between the incidence of HA-MRSA and the use of alcohol-based hand rub. Overall, the model explained 40.5% of the variance in the monthly incidence of MRSA. CONCLUSION: This study showed that admission of patients with MRSA, the use of antibiotics and infection control practices contributed to the incidence of HA-MRSA. This suggests that efforts should be focused on high compliance with hand disinfection. These results also raise concerns about the use of gloves when caring for patients with MRSA.
- Subjects :
- Antibiotics
Hospitals, University
MESH: Infection Control
0302 clinical medicine
[ SDV.MP ] Life Sciences [q-bio]/Microbiology and Parasitology
Medicine
Infection control
030212 general & internal medicine
MESH: Incidence
MESH : Anti-Bacterial Agents
0303 health sciences
Cross Infection
Incidence (epidemiology)
Incidence
General Medicine
Staphylococcal Infections
University hospital
MESH : Incidence
3. Good health
Anti-Bacterial Agents
Infectious Diseases
[SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology
France
Negative correlation
MESH : Cross Infection
Microbiology (medical)
Methicillin-Resistant Staphylococcus aureus
medicine.medical_specialty
medicine.drug_class
MESH: Staphylococcal Infections
MESH: Methicillin-Resistant Staphylococcus aureus
03 medical and health sciences
Internal medicine
MESH: Anti-Bacterial Agents
Humans
MESH : Methicillin-Resistant Staphylococcus aureus
Intensive care medicine
MESH : France
Hand disinfection
MESH : Hospitals, University
Hand rub
MESH: Hospitals, University
Infection Control
MESH: Humans
MESH : Infection Control
030306 microbiology
business.industry
MRSA colonization
MESH : Humans
MESH: Cross Infection
biochemical phenomena, metabolism, and nutrition
bacterial infections and mycoses
MESH: France
MESH : Staphylococcal Infections
business
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- J Hosp Infect, J Hosp Infect, 2012, 82 (3), pp.164-9. ⟨10.1016/j.jhin.2012.07.013⟩, J Hosp Infect, 2012, 82 (3), pp.164-9. 〈10.1016/j.jhin.2012.07.013〉
- Accession number :
- edsair.doi.dedup.....bb1656540eb65e35b0ab546e58ca5152