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P-222 Analysis of tumour contours and radiotherapy planning of 'on-trial' patients undergoing chemoradiotherapy (CRT) in SCALOP trial: does pre-trial Radiotherapy Quality Assurance (RTQA) improve the quality of 'on-trial' radiotherapy?

Authors :
John Staffurth
S. Mukherjee
Emiliano Spezi
Emmanouil Fokas
G. Joseph
Lisette Sheena Nixon
K. Chu
Chris Nicholas Hurt
Neel Patel
Ross A. Abrams
Source :
Europe PubMed Central
Publication Year :
2016
Publisher :
Elsevier BV, 2016.

Abstract

The SCALOP trial tested the safety and efficacy of gemcitabine (Gem) versus capecitabine (Cap) based CRT following induction chemotherapy and showed that GemRT was associated with greater toxicity and worse survival1. The evaluation of investigator-delineated volumes and plan assessment from the pre-trial RTQA program using a single benchmark case showed considerable variation in gross tumour volume (GTV) outlining but no major deviations in other aspects of RT planning.

Details

ISSN :
09237534
Volume :
27
Database :
OpenAIRE
Journal :
Annals of Oncology
Accession number :
edsair.doi.dedup.....bb1df02c7e9256752b6becd7cdc6a82c
Full Text :
https://doi.org/10.1093/annonc/mdw199.214