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Efficacy of single-dose azithromycin in treatment of acute otitis media in children after a baseline tympanocentesis

Authors :
Judy A. Krogstad
Jean Chow
Chandra Khurana
P. Fernández
Richard H. Schwartz
Mary M. Aspin
Michael W. Dunne
Adib Rodriguez
Sergio L. Vargas
Paz Emparanza
Irmeli Roine
Adriano Arguedas Mohs
John K. Podgore
Samuel Mclinn
Jeffrey L. Blumer
Antonio Arrieta
Mark M. Blatter
Garth D. Ehrlich
Willis M. Gooch
Source :
Antimicrobial agents and chemotherapy. 47(8)
Publication Year :
2003

Abstract

Children with acute otitis media underwent tympanocentesis and were given a single dose of 30 mg of azithromycin/kg of body weight. At day 28, the overall clinical cure rate was 206 of 242 (85%). Clinical cure rates for patients infected with Streptococcus pneumoniae (67 of 76; 88%) and Haemophilus influenzae (28 of 44; 64%) were consistent with historical rates for the 5-day dosing regimen.

Details

ISSN :
00664804
Volume :
47
Issue :
8
Database :
OpenAIRE
Journal :
Antimicrobial agents and chemotherapy
Accession number :
edsair.doi.dedup.....bbb0a5da15a0fa06564f17e7b8ca468b