Comparative Study of the Standard Fluorescent Antibody to Membrane Antigen (FAMA) Assay and a Flow Cytometry-Adapted FAMA Assay To Assess Immunity to Varicella-Zoster Virus

Authors :: Lily Yin Weckx
Anne A. Gershon
Manuel Mindlin Lafer
M.I. de Moraes-Pinto
Sharon Steinberg
P. LaRussa
Aaron F. Garretson
Universidade Federal de São Paulo (UNIFESP)
Columbia Univ
Source :: Repositório Institucional da UNIFESP, Universidade Federal de São Paulo (UNIFESP), instacron:UNIFESP
Publication Year :: 2011
Publisher :: American Society for Microbiology, 2011.
Abstract: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) A flow cytometry-adapted fluorescent antibody to membrane antigen (FAMA) assay to detect IgG antibodies against varicella-zoster virus (VZV) was developed and tested in 62 serum samples, showing 90.32% accuracy obtained from a receiver operating characteristic (ROC) curve with a 0.9125 (95% confidence interval [CI], 0.829 to 1.00) area below the curve compared to the result with standard FAMA. Fed Univ São Paulo UNIFESP EPM, Div Pediat Infect Dis, BR-04040000 São Paulo, Brazil Columbia Univ, Dept Pediat, Coll Phys & Surg, New York, NY 10027 USA Fed Univ São Paulo UNIFESP EPM, Div Pediat Infect Dis, BR-04040000 São Paulo, Brazil CAPES: 0108-08-1 Web of Science

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