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Characteristics of Optic Disc and Visual Field Changes in Patients with Thyroid-Associated Orbitopathy and Open-Angle Glaucoma
- Source :
- Journal of Clinical Medicine, Journal of Clinical Medicine, Vol 10, Iss 3839, p 3839 (2021), Volume 10, Issue 17
- Publication Year :
- 2021
- Publisher :
- MDPI AG, 2021.
-
Abstract
- This study aimed to characterize the changes in the visual field (VF) patterns and disc morphology of patients with thyroid-associated orbitopathy (TAO) and open-angle glaucoma (OAG). A retrospective review of the medical records at the Tri-Service General Hospital in Taiwan identified 396 eyes of 198 patients with thyroid-associated glaucoma. A final follow-up of VF examination in 140 eyes revealed 114 eyes with VF defects, indicating disease progression. The characteristics of and changes in disc morphology, optical coherence tomography findings, and VF defects were statistically analyzed. The most common VF defects at the initial diagnosis and the end of the follow-up period were inferior partial arcuate (17%) and paracentral (15%) defects, respectively. The most common VF defect in patients with unspecific disc signs was an unspecific scotoma (13%). The most common optic disc feature was disc cupping (51%), followed by parapapillary atrophy (48%). The most frequent location of nerve fiber layer thinning was the inferotemporal region (48%). VF defects showed a significantly more pronounced progression in the non-nerve fiber bundle group than in the nerve fiber bundle group (p &lt<br />0.001). This study details the characteristics and progression of disc morphology and VF defects in patients with TAO and OAG.
- Subjects :
- medicine.medical_specialty
genetic structures
Open angle glaucoma
Nerve fiber layer
open-angle glaucoma
Glaucoma
Article
Optical coherence tomography
Ophthalmology
medicine
hyperthyroidism
medicine.diagnostic_test
business.industry
Blind spot
Thyroid
thyroid eye disease
General Medicine
medicine.disease
eye diseases
Visual field
medicine.anatomical_structure
thyroid-associated orbitopathy
Medicine
sense organs
business
Optic disc
Subjects
Details
- ISSN :
- 20770383
- Volume :
- 10
- Database :
- OpenAIRE
- Journal :
- Journal of Clinical Medicine
- Accession number :
- edsair.doi.dedup.....bc1b89acc5bde6d48df7695280484c6d