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Prognostic value of the absolute lymphocyte count in patients admitted for acute heart failure
- Source :
- Journal of Cardiovascular Medicine. 18:859-865
- Publication Year :
- 2017
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2017.
-
Abstract
- Low relative lymphocyte count is an important prognostic marker in acute heart failure (AHF); however, it could be influenced by other abnormalities in white cells count. Our purpose is to evaluate if low absolute lymphocyte count (ALC) is an independent predictor of events in patients with AHF. In a retrospective analysis, we included 309 patients with AHF, divided into two groups according to the median value of ALC at admission (1410 cells/μl). The primary end point was all-cause mortality or urgent heart transplantation within 1 year. Patients with low ALC were older and had more comorbidity, namely atrial fibrillation, chronic kidney disease, chronic obstructive pulmonary disease and anemia. Low ALC was associated with higher all-cause mortality or urgent heart transplantation at 1 year (24.3 vs 13.0%; P = 0.012). In a multivariable model, the independent predictors of mortality at 1 year were ALC 1410 cells/μl or less at admission [hazard ratio 2.04; CI (confidence interval) 95% (1.06–3.95); P = 0.033], age [hazard ratio 1.08; CI 95% (1.04–1.12); P
- Subjects :
- Male
medicine.medical_specialty
Anemia
medicine.medical_treatment
Comorbidity
030204 cardiovascular system & hematology
03 medical and health sciences
0302 clinical medicine
Predictive Value of Tests
Cause of Death
Internal medicine
Humans
Medicine
Hospital Mortality
Lymphocyte Count
Renal Insufficiency
030212 general & internal medicine
Aged
Proportional Hazards Models
Retrospective Studies
Aged, 80 and over
Heart Failure
Heart transplantation
business.industry
Proportional hazards model
Sodium
Hazard ratio
Atrial fibrillation
General Medicine
Middle Aged
medicine.disease
Surgery
Hospitalization
Italy
Creatinine
Heart failure
Predictive value of tests
Acute Disease
Multivariate Analysis
Cardiology
Heart Transplantation
Female
Cardiology and Cardiovascular Medicine
business
Kidney disease
Subjects
Details
- ISSN :
- 15582027
- Volume :
- 18
- Database :
- OpenAIRE
- Journal :
- Journal of Cardiovascular Medicine
- Accession number :
- edsair.doi.dedup.....bc3b3cf12e893450d00b1d8a19e065a7