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Photo-magnetic Imaging: Resolving Optical Contrast at MRI resolution
- Publication Year :
- 2013
-
Abstract
- In this paper, we establish the mathematical framework of a novel imaging technique, namely photo-magnetic imaging (PMI). PMI uses a laser to illuminate biological tissues and measure the induced temperature variations using magnetic resonance imaging (MRI). PMI overcomes the limitation of conventional optical imaging and allows imaging of the optical contrast at MRI spatial resolution. The image reconstruction for PMI, using a finite-element-based algorithm with an iterative approach, is presented in this paper. The quantitative accuracy of PMI is investigated for various inclusion sizes, depths and absorption values. Then, a comparison between conventional diffuse optical tomography (DOT) and PMI is carried out to illustrate the superior performance of PMI. An example is presented showing that two 2 mm diameter inclusions embedded 4.5 mm deep and located side by side in a 25 mm diameter circular geometry medium are recovered as a single 6 mm diameter object with DOT. However, these two objects are not only effectively resolved with PMI, but their true concentrations are also recovered successfully.
- Subjects :
- Photon
Materials science
Hot Temperature
Optical Phenomena
Iterative reconstruction
Article
law.invention
Absorption
Diffusion
Motion
Optics
law
medicine
Radiology, Nuclear Medicine and imaging
Absorption (electromagnetic radiation)
Image resolution
Photons
Radiological and Ultrasound Technology
medicine.diagnostic_test
business.industry
Phantoms, Imaging
Computer Science::Information Retrieval
Resolution (electron density)
Magnetic resonance imaging
Computer Science::Computation and Language (Computational Linguistics and Natural Language and Speech Processing)
Models, Theoretical
Laser
Magnetic Resonance Imaging
Diffuse optical imaging
business
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....bc76437b7a9d9365e9bee173b05da1d7