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Super-size flies

Authors :
Norbert Perrimon
Meghana M. Kulkarni
Source :
Cell Metabolism. 1:288-290
Publication Year :
2005
Publisher :
Elsevier BV, 2005.

Abstract

The increasing prevalence of obesity and other nutrition-related chronic diseases has prompted considerable efforts to understand their pathogenesis and treatment. One experimental approach is to overexpress, inactivate, or manipulate specific genes that regulate energy metabolism and fat storage. Many such techniques are fully established, routine tools in Drosophila and C. elegans, which provide elegant models for dissecting endocrine problems and metabolic pathways.

Details

ISSN :
15504131
Volume :
1
Database :
OpenAIRE
Journal :
Cell Metabolism
Accession number :
edsair.doi.dedup.....bcc924e70f2d8ccac235824916785ccc
Full Text :
https://doi.org/10.1016/j.cmet.2005.04.008