Clinical impact of enhanced cytokine clearance with sustained high-efficiency daily diafiltration using a mediator-adsorbing membrane (SHEDD-fA) in patients with severe sepsis

SHEDD-fA is an effective modality that makes the best use of three principles in the treatment of severe sepsis: diffusion, convection and adsorption. We reported the efficacy of SHEDD-fA for the treatment of severe sepsis at the 31st ISICEM 2011 [1]. Here we present the blood clearance (CL) of seven important cytokines with SHEDD-fA.