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Hyperlocalized Measures of Air Pollution and Preeclampsia in Oakland, California
- Source :
- Environ Sci Technol, Environmental science & technology, vol 55, iss 21
- Publication Year :
- 2021
-
Abstract
- Exposure to nitrogen dioxide (NO(2)), black carbon (BC), and ultrafine particles (UFP) during pregnancy may increase risk of preeclampsia, but previous studies have not assessed hyper-localized differences in pollutant levels which may cause exposure misclassification. We used data from Google Street View cars with mobile air monitors that repeatedly sampled NO(2), BC, and UFP every 30-meters in Downtown and West Oakland neighborhoods during 2015–2017. Data were linked to electronic health records of pregnant women in the 2014-2016 Sutter Health population who resided within 120-meters of monitoring data (N=1,095) to identify preeclampsia cases. We used G-computation with log-binomial regression to estimate risk differences (RD) associated with hypothetical interventions reducing pollutant levels to 25(th) percentiles observed in our sample on preeclampsia risk, overall and stratified by race/ethnicity. Prevalence of preeclampsia was 6.8%. Median (interquartile range) levels of NO(2), BC, and UFP were 10.8 ppb (9.0, 13.0), 0.34 μg/m(3) (0.27, 0.42), and 29.2 # × 10(3)/cm(3) (26.6, 32.6), respectively. Changes in the risk of preeclampsia achievable by limiting each pollutant to the 25(th) percentile was NO(2) RD =−1.5 per 100 women (95% confidence interval (CI): −2.5, −0.5); BC RD=−1.0 (95% CI: −2.2, 0.02); and UFP RD = −0.5 (95% CI: −1.8, 0.7). Estimated effects were largest for non-Latina Black mothers: NO(2) RD=−2.8 (95% CI: −5.2, −0.3) and BC RD=−3.0 (95% CI: −6.4, 0.4).
- Subjects :
- Percentile
nitrogen dioxide
Population
air pollution
Nitrogen Dioxide
Air pollution
medicine.disease_cause
black carbon
maternal health
California
Article
Preeclampsia
Pre-Eclampsia
Interquartile range
Clinical Research
Pregnancy
Air Pollution
Ultrafine particle
medicine
Environmental Chemistry
Humans
education
education.field_of_study
Air Pollutants
business.industry
pregnancy complications
Contraception/Reproduction
Prevention
hypertensive disorders of pregnancy
General Chemistry
Environmental Exposure
medicine.disease
Confidence interval
ultrafine particles
Good Health and Well Being
Female
Particulate Matter
business
Environmental Sciences
Demography
Subjects
Details
- ISSN :
- 15205851
- Volume :
- 55
- Issue :
- 21
- Database :
- OpenAIRE
- Journal :
- Environmental sciencetechnology
- Accession number :
- edsair.doi.dedup.....bd142d84e73e84df5e9e7e1c9de753cd