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A selective and light-up fluorescent probe for β-galactosidase activity detection and imaging in living cells based on an AIE tetraphenylethylene derivative
- Source :
- Chemical communications (Cambridge, England). 53(32)
- Publication Year :
- 2017
-
Abstract
- An aggregation induced emission (AIE) based bioimaging probe, TPE-Gal, was designed for light-up imaging of β-galactosidase in living cells. The applicability of TPE-Gal in imaging endogenous β-galactosidase activity was confirmed in OVCAR-3 cells.
- Subjects :
- Light
Cell Survival
Nanotechnology
02 engineering and technology
010402 general chemistry
01 natural sciences
Catalysis
chemistry.chemical_compound
Structure-Activity Relationship
Cell Line, Tumor
Stilbenes
Materials Chemistry
Humans
Aggregation-induced emission
Fluorescent Dyes
Ovarian Neoplasms
Dose-Response Relationship, Drug
Molecular Structure
Optical Imaging
Metals and Alloys
Galactose
Galactosidase activity
General Chemistry
Tetraphenylethylene
021001 nanoscience & nanotechnology
beta-Galactosidase
Fluorescence
0104 chemical sciences
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
Spectrometry, Fluorescence
chemistry
Ceramics and Composites
Biophysics
Female
Light Up
0210 nano-technology
Derivative (chemistry)
HeLa Cells
Subjects
Details
- ISSN :
- 1364548X
- Volume :
- 53
- Issue :
- 32
- Database :
- OpenAIRE
- Journal :
- Chemical communications (Cambridge, England)
- Accession number :
- edsair.doi.dedup.....bd5bf1a931122ca87f6f47c5d148b74d