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Protection against severe COVID-19 after second booster dose of adapted bivalent (original/Omicron BA.4-5) mRNA vaccine in persons ≥ 60 years, by time since infection, Italy, 12 September to 11 December 2022
- Source :
- Eurosurveillance. 28
- Publication Year :
- 2023
- Publisher :
- European Centre for Disease Control and Prevention (ECDC), 2023.
-
Abstract
- Effectiveness against severe COVID-19 of a second booster dose of the bivalent (original/BA.4–5) mRNA vaccine 7–90 days post-administration, relative to a first booster dose of an mRNA vaccine received ≥ 120 days earlier, was ca 60% both in persons ≥ 60 years never infected and in those infected > 6 months before. Relative effectiveness in those infected 4–6 months earlier indicated no significant additional protection (10%; 95% CI: −44 to 44). A second booster vaccination 6 months after the latest infection may be warranted.
Details
- ISSN :
- 15607917
- Volume :
- 28
- Database :
- OpenAIRE
- Journal :
- Eurosurveillance
- Accession number :
- edsair.doi.dedup.....bd77669727b3d2491ca7ff00477a3e1f