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Dietary Fiber and Metabolic Syndrome: A Meta-Analysis and Review of Related Mechanisms
- Source :
- Nutrients, Nutrients, Vol 10, Iss 1, p 24 (2017)
- Publication Year :
- 2017
- Publisher :
- MDPI AG, 2017.
-
Abstract
- (1) Background: Dietary fiber intake may provide beneficial effects on the components of metabolic syndrome (MetS); however, observational studies reported inconsistent results for the relationship between dietary fiber intake and MetS risk. We conducted a meta-analysis to quantify previous observational studies and a narrative review to summarize mechanisms involved in the potential relationship. (2) Methods: The literature was searched on PubMed and Web of Science until 28 November 2017. A random-effects model was used to calculate the summary risk estimates. Eleven cross-sectional studies and three cohort studies were included in the meta-analysis. Results from the original studies were reported as odds ratios (ORs) or relative ratios (RRs) of the MetS associated with different levels of dietary fiber intake, and the ORs/RRs comparing the highest with lowest categories of the intake were pooled. (3) Results: For the cross-sectional studies, the pooled OR was 0.70 (95% confidence interval (CI): 0.61–0.82) with evidence of high heterogeneity (I2 = 74.4%, p < 0.001) and publication bias (p for Egger’s test < 0.001). After removing four studies, results remained significant (OR = 0.67, 95% CI: 0.58–0.78) and the heterogeneity was largely reduced (I2 = 32.4%, p = 0.181). For the cohort studies, the pooled RR was 0.86 (95% CI: 0.70–1.06). (4) Conclusion: Although the meta-analysis suggests an inverse association between dietary fiber intake and risk of MetS, and the association was supported by a wide range of mechanism studies, the findings are limited by insufficient cohort data. More prospective studies are needed to further verify the association between dietary fiber intake and the risk of MetS.
- Subjects :
- Dietary Fiber
0301 basic medicine
medicine.medical_specialty
lcsh:TX341-641
Review
Recommended Dietary Allowances
03 medical and health sciences
Risk Factors
Internal medicine
Odds Ratio
Humans
Medicine
Prospective cohort study
Metabolic Syndrome
mechanisms
030109 nutrition & dietetics
Nutrition and Dietetics
business.industry
Odds ratio
Publication bias
Protective Factors
medicine.disease
Confidence interval
meta-analysis
Meta-analysis
Cohort
Metabolic syndrome
business
lcsh:Nutrition. Foods and food supply
Food Science
Cohort study
Subjects
Details
- ISSN :
- 20726643
- Volume :
- 10
- Database :
- OpenAIRE
- Journal :
- Nutrients
- Accession number :
- edsair.doi.dedup.....bde3a4928ad74043b9629715bc2b513e