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In Vivo Imaging-Based Techniques for Early Diagnosis of Oral Potentially Malignant Disorders—Systematic Review and Meta-Analysis
In Vivo Imaging-Based Techniques for Early Diagnosis of Oral Potentially Malignant Disorders—Systematic Review and Meta-Analysis
- Source :
- International Journal of Environmental Research and Public Health, Vol 18, Iss 11775, p 11775 (2021), International Journal of Environmental Research and Public Health
- Publication Year :
- 2021
- Publisher :
- MDPI AG, 2021.
-
Abstract
- Objectives: Oral potentially malignant disorders (OPMDs) are lesions that may undergo malignant transformation to oral cancer. The early diagnosis and surveillance of OPMDs reduce the morbidity and mortality of patients. Diagnostic techniques based on medical images analysis have been developed to diagnose clinical conditions. This systematic review and meta-analysis aimed to evaluate the efficacy of imaging-based techniques compared to the gold standard of histopathology to assess their ability to correctly identify the presence of OPMDs. Design: Literature searches of free text and MeSH terms were performed using MedLine (PubMed), Scopus, Google Scholar, and the Cochrane Library (from 2000 to 30 June 2020). The keywords used in the search strategy were: (“oral screening devices” or “autofluorescence” or “chemiluminescence” or “optical imaging” or “imaging technique”) and (“oral dysplasia” or “oral malignant lesions” or “oral precancerosis”). Results: The search strategy identified 1282 potential articles. After analyzing the results and applying the eligibility criteria, the remaining 43 papers were included in the qualitative synthesis, and 34 of these were included in the meta-analysis. Conclusions: None of the analyzed techniques based on assessing oral images can replace the biopsy. Further studies are needed to explore the role of techniques-based imaging analysis to identify an early noninvasive screening method.
- Subjects :
- medicine.medical_specialty
diagnosis
Health, Toxicology and Mutagenesis
Biopsy
imaging-based techniques
potentially malignant oral lesions
OPMD
MEDLINE
Review
Cochrane Library
medicine
Humans
Early Detection of Cancer
Oral Dysplasia
medicine.diagnostic_test
business.industry
Public Health, Environmental and Occupational Health
Cancer
Gold standard (test)
medicine.disease
Meta-analysis
Medicine
Mouth Neoplasms
Radiology
business
Mouth Diseases
Precancerous Conditions
Preclinical imaging
Subjects
Details
- Language :
- English
- ISSN :
- 16617827 and 16604601
- Volume :
- 18
- Issue :
- 11775
- Database :
- OpenAIRE
- Journal :
- International Journal of Environmental Research and Public Health
- Accession number :
- edsair.doi.dedup.....bde6e5095ea9089be6642241094e6fa6