Juvenile Acinar Atrophy of the Pancreas of a Dog

A dog with juvenile acinar atrophy of the pancreas had degranulation and loss of the acinar cells. Transitional features from normal to degranulation were seen. Electron microscopically, the atrophic pancreas mainly consisted of epithelial cells of duct system, islet cells and multivesicular cells. Juvenile atrophy of the canine pancreas [1] is characterized by pancreatic enzyme deficiency in young dogs in association with a non-inflammatory lesion of the pancreas. Clinically there is polyphagia, weight loss, steatorrhea, diarrhea and coprohagia.