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Peripapillary hyperreflective ovoid mass-like structures (PHOMS) in children
- Source :
- Eye (Lond)
- Publication Year :
- 2021
- Publisher :
- Springer Science and Business Media LLC, 2021.
-
Abstract
- Background To analyse structural characteristics and perifoveal/peripapillary vasculature by OCT in children with peripapillary hyperreflective ovoid mass-like structures (PHOMS) and compare the results with those of normal subjects. Methods Forty-five patients (84 eyes) under 18 years old with blurry disc margin were evaluated with spectral domain-OCT and swept course-OCT. Patients were divided into four groups, according to presence of PHOMS and then the size of the existing PHOMS. Eyes with visible optic disc drusen (ODD) were not included. Foveal avascular zone (FAZ) and vessel densities from macula and optic disc area were assessed and potential associations between vessel density and structural parameters, such as peripapillary retinal nerve fibre layer (pRNFL), and macular ganglion cell and inner plexiform layer (mGCIPL) thickness, were analysed. Results Among 45 patients (eighty-four eyes), coexisting buried ODD were found only in eyes with PHOMS. The scleral canal diameter was significantly smaller in PHOMS positive eyes compared to control eyes. Vessel density measurements from the papillary, peripapillary and optic nerve head (ONH) regions in the large PHOMS group were significantly lower compared to the control group (papillary; P = 0.014, peripapillary; P = 0.001, ONH; P = 0.046). FAZ area and macular vessel densities showed no difference compared to normal eyes in all three PHOMS groups. pRNFL and mGCIPL thickness did not differ among four groups and correlations were also not significant. Conclusions Children with PHOMS have smaller scleral canal and can entail buried ODD. Vessel densities of optic disc area in large PHOMS eyes are significantly lower than in normal eyes.
- Subjects :
- medicine.medical_specialty
Adolescent
genetic structures
Optic Disk
Article
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Ophthalmology
medicine
Humans
Macula Lutea
Child
Optic Disk Drusen
business.industry
Retinal
Foveal avascular zone
Inner plexiform layer
medicine.disease
Optic disc drusen
eye diseases
Ganglion
medicine.anatomical_structure
chemistry
030221 ophthalmology & optometry
Optic nerve
Ovoid
sense organs
business
Sclera
Tomography, Optical Coherence
030217 neurology & neurosurgery
Optic disc
Subjects
Details
- ISSN :
- 14765454 and 0950222X
- Volume :
- 36
- Database :
- OpenAIRE
- Journal :
- Eye
- Accession number :
- edsair.doi.dedup.....be6e1e91ea66f9efc018c24dd21d4ce1