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Incidence of postoperative nausea and vomiting following gynecological laparoscopy: A comparison of standard anesthetic technique and propofol infusion
- Source :
- Acta Anaesthesiologica Taiwanica.
- Publication Year :
- 2016
- Publisher :
- Elsevier BV, 2016.
-
Abstract
- To determine the safety, efficacy, and feasibility of propofol-based anesthesia in gynecological laparoscopies in reducing incidences of postoperative nausea and vomiting compared to a standard anesthesia using thiopentone/isoflurane.Randomized single-blind (for anesthesia techniques used) and double-blind (for postoperative assessment) controlled trial.Operation theater, postanesthesia recovery room, teaching hospital.Sixty ASA (American Society of Anesthesiologists) I and II female patients (aged 20-60 years) scheduled for gynecological laparoscopy were included in the study.Patients in Group A received standard anesthesia with thiopentone for induction and maintenance with isoflurane-fentanyl, and those in Group B received propofol for induction and maintenance along with fentanyl. All patients received nitrous oxide, vecuronium, and neostigmine/glycopyrrolate. No patient received elective preemptive antiemetic, but patients did receive it after more than one episode of vomiting.Assessment for incidence of postoperative nausea and vomiting as well as other recovery parameters were carried out over a period of 24 hours.Six patients (20%) in Group A and seven patients (23.3%) in Group B experienced nausea. Two patients (6.66%) in Group B had vomiting versus 12 (40%) in Group A (p0.05). Overall, the incidence of emesis was 60% and 30% in Groups A and B, respectively (p0.05). All patients in Group B had significantly faster recovery compared with those in Group A. No patient had any overt cardiorespiratory complications.Propofol-based anesthesia was associated with significantly less postoperative vomiting and faster recovery compared to standard anesthesia in patients undergoing gynecological laparoscopy.
- Subjects :
- Adult
medicine.medical_specialty
Nausea
medicine.drug_class
Fentanyl
Young Adult
03 medical and health sciences
Gynecologic Surgical Procedures
0302 clinical medicine
030202 anesthesiology
medicine
Humans
Antiemetic
Anesthesia
030212 general & internal medicine
Propofol
business.industry
Incidence
General Medicine
Middle Aged
Surgery
Neostigmine
Anesthesiology and Pain Medicine
Isoflurane
Postoperative Nausea and Vomiting
Vomiting
Female
Laparoscopy
medicine.symptom
business
Anesthetics, Intravenous
Postoperative nausea and vomiting
medicine.drug
Subjects
Details
- ISSN :
- 18754597
- Database :
- OpenAIRE
- Journal :
- Acta Anaesthesiologica Taiwanica
- Accession number :
- edsair.doi.dedup.....bf67deaaf20c3b0bc14760c81f7eafc0
- Full Text :
- https://doi.org/10.1016/j.aat.2016.10.002