Progressive substitution of posttransplant cyclophosphamide with bendamustine: A phase I study in haploidentical bone marrow transplantation

Authors :: Emmanuel Katsanis
Richard J. Simpson
Keri Renee Maher
Denise J. Roe
Source :: EJHaem. 1(1)
Publication Year :: 2020
Abstract: We have initiated a single center phase I study in patients with hematologic malignancies progressively substituting day +4 posttransplant cyclophosphamide (PT-CY) with bendamustine (PT-BEN) following myeloablative conditioning (MAC) and T-cell replete haploidentical bone marrow transplantation (haplo-BMT). We report herein our interim analysis of our first three cohorts PT-CY (mg/kg)/PT-BEN (mg/m

Subjects :: Bendamustine
medicine.medical_specialty
Bone marrow transplantation
Cyclophosphamide
business.industry
Substitution (logic)
medicine
Urology
business
medicine.drug
Phase i study

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