Back to Search
Start Over
Low adherence to colonoscopy in the screening of first-degree relatives of patients with colorectal cancer
Low adherence to colonoscopy in the screening of first-degree relatives of patients with colorectal cancer
- Source :
- Gut. 56:1714-1718
- Publication Year :
- 2007
- Publisher :
- BMJ, 2007.
-
Abstract
- Colonoscopy is one of the methods of choice for screening relatives of patients with colorectal cancer.To evaluate the rate of adherence to colonoscopy in first-degree relatives of patients with colorectal cancer and describe the lesions found.A prospective, cross-sectional, multicentre, nationwide study was conducted. The study population was composed of first-degree relatives of patients with colorectal cancer selected randomly from the EPICOLON study. Seventy-four index patients were included. These had 342 living first-degree relatives (parents, siblings and children), of whom 281 were interviewed.The adherence rate was 38% (107/281). Adherence was greater in families with a higher degree of familial aggregation for colorectal cancer (88.9% for Amsterdam vs 33.3% for Bethesda and sporadic cancer; p0.05), an index patient aged under 65 years (60% for patients65 years vs 32.9% for patientsor=65 years; p0.05) and an index patient who was female (46.2% for women vs 31% for men; p = 0.28). Adherence was also greater in relatives under 65 years (54% in patients65 years vs 18% in patientsor=65 years; p = 0.05), in female relatives (49% in female relatives vs 27.3% in male relatives; p0.05) and in siblings and children (40% in siblings and children vs 13% in parents; p0.05). Lesions were found in 26% (28/107) of the study population. Nine (8.4%) individuals had a total of 18 advanced lesions.These results indicate that adherence to colonoscopy in our population of first-degree relatives was low. The adherence was more frequently associated with a higher degree of familial aggregation, a relative age of under 65 years, a sibling or offspring relationship, and female sex.
- Subjects :
- Adult
Male
medicine.medical_specialty
Colorectal cancer
education
Population
Colonoscopy
Gastroenterology
Sex Factors
Internal medicine
medicine
Humans
Mass Screening
Genetic Predisposition to Disease
Prospective Studies
First-degree relatives
Mass screening
Aged
education.field_of_study
medicine.diagnostic_test
business.industry
Age Factors
Cancer
Family aggregation
Middle Aged
medicine.disease
humanities
Spain
Commentary
Patient Compliance
Population study
Female
Colorectal Neoplasms
business
Subjects
Details
- ISSN :
- 00175749
- Volume :
- 56
- Database :
- OpenAIRE
- Journal :
- Gut
- Accession number :
- edsair.doi.dedup.....bfd77e9856d279e4e47404d2dcf4b5b5
- Full Text :
- https://doi.org/10.1136/gut.2007.120709