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Molecular Imaging with MRI: Potential Application in Pancreatic Cancer
- Source :
- BioMed Research International, BioMed Research International, Vol 2015 (2015)
- Publication Year :
- 2015
- Publisher :
- Hindawi Limited, 2015.
-
Abstract
- Despite the variety of approaches that have been improved to achieve a good understanding of pancreatic cancer (PC), the prognosis of PC remains poor, and the survival rates are dismal. The lack of early detection and effective interventions is the main reason. Therefore, considerable ongoing efforts aimed at identifying early PC are currently being pursued using a variety of methods. In recent years, the development of molecular imaging has made the specific targeting of PC in the early stage possible. Molecular imaging seeks to directly visualize, characterize, and measure biological processes at the molecular and cellular levels. Among different imaging technologies, the magnetic resonance (MR) molecular imaging has potential in this regard because it facilitates noninvasive, target-specific imaging of PC. This topic is reviewed in terms of the contrast agents for MR molecular imaging, the biomarkers related to PC, targeted molecular probes for MRI, and the application of MRI in the diagnosis of PC.
- Subjects :
- lcsh:Medicine
Early detection
Review Article
Bioinformatics
Sensitivity and Specificity
General Biochemistry, Genetics and Molecular Biology
Effective interventions
Pancreatic cancer
Image Interpretation, Computer-Assisted
Biomarkers, Tumor
medicine
Humans
Stage (cooking)
Evidence-Based Medicine
General Immunology and Microbiology
medicine.diagnostic_test
business.industry
lcsh:R
Reproducibility of Results
Magnetic resonance imaging
General Medicine
Prognosis
medicine.disease
Magnetic Resonance Imaging
Molecular Imaging
Pancreatic Neoplasms
Feasibility Studies
Molecular imaging
Molecular probe
business
Subjects
Details
- ISSN :
- 23146141 and 23146133
- Volume :
- 2015
- Database :
- OpenAIRE
- Journal :
- BioMed Research International
- Accession number :
- edsair.doi.dedup.....bfd7b3392e4a1e2665b9f72d0b7599f8