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Preoperative staging of colorectal cancer: CT vs. integrated FDG PET/CT
- Source :
- Abdominal Imaging. 33:270-277
- Publication Year :
- 2007
- Publisher :
- Springer Science and Business Media LLC, 2007.
-
Abstract
- Accurate preoperative staging is essential in determining the optimal therapeutic planning for individual patients. The computed tomography (CT) in the preoperative staging of colorectal cancer, even if controversial, may be useful for planning surgery and/or neoadjuvant therapy, particularly when local tumor extension into adjacent organs or distant metastases are detected. There have been significant changes in the CT technology with the advent of multi-detector row CT (MDCT) scanner. Advances in CT technology have raised interest in the potential role of CT for detection and staging of colorectal cancer. In recent studies, MDCT with MPR images has shown promising accuracy in the evaluation of local extent and nodal involvement of colorectal cancer. Combined PET/CT images have significant advantages over either alone because it provides both functional and anatomical data. Therefore, it is natural to expect that PET/CT would improve the accuracy of preoperative staging of colorectal cancer. The most significant additional information provided by PET/CT relates to the accurate detection of distant metastases. For the evaluation of patients with colorectal cancer, CT has relative advantages over PET/CT in regard to the depth of tumor invasion through the wall, extramural extension, and regional lymph node metastases. PET/CT should be performed on selected patients with suggestive but inconclusive metastatic lesions with CT. In addition, PET/CT with dedicated CT protocols, such as contrast-enhanced PET/CT and PET/CT colonography, may replace the diagnostic CT for the preoperative staging of colorectal cancer.
- Subjects :
- medicine.medical_specialty
Colorectal cancer
Urology
medicine.medical_treatment
Sensitivity and Specificity
Preoperative care
Fluorodeoxyglucose F18
Internal medicine
Preoperative Care
medicine
Humans
Radiology, Nuclear Medicine and imaging
Neoplasm Metastasis
Lymph node
Neoadjuvant therapy
Neoplasm Staging
Radiological and Ultrasound Technology
medicine.diagnostic_test
business.industry
Gastroenterology
Cancer
General Medicine
Hepatology
Prognosis
medicine.disease
medicine.anatomical_structure
Positron emission tomography
Lymphatic Metastasis
Radiology
Tomography
Radiopharmaceuticals
Colorectal Neoplasms
Tomography, X-Ray Computed
business
Nuclear medicine
Tomography, Emission-Computed
Subjects
Details
- ISSN :
- 14320509 and 09428925
- Volume :
- 33
- Database :
- OpenAIRE
- Journal :
- Abdominal Imaging
- Accession number :
- edsair.doi.dedup.....c0808e87bd8714a5fdec8418f123461e