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Prediction of anemia and estimation of hemoglobin concentration using a smartphone camera
- Source :
- PLoS ONE, Vol 16, Iss 7, p e0253495 (2021), PLoS ONE
- Publication Year :
- 2021
- Publisher :
- Public Library of Science (PLoS), 2021.
-
Abstract
- Anemia, defined as a low hemoglobin concentration, has a large impact on the health of the world’s population. We describe the use of a ubiquitous device, the smartphone, to predict hemoglobin concentration and screen for anemia. This was a prospective convenience sample study conducted in Emergency Department (ED) patients of an academic teaching hospital. In an algorithm derivation phase, images of both conjunctiva were obtained from 142 patients in Phase 1 using a smartphone. A region of interest targeting the palpebral conjunctiva was selected from each image. Image-based parameters were extracted and used in stepwise regression analyses to develop a prediction model of estimated hemoglobin (HBc). In Phase 2, a validation model was constructed using data from 202 new ED patients. The final model based on all 344 patients was tested for accuracy in anemia and transfusion thresholds. Hemoglobin concentration ranged from 4.7 to 19.6 g/dL (mean 12.5). In Phase 1, there was a significant association between HBc and laboratory-predicted hemoglobin (HBl) slope = 1.07 (CI = 0.98–1.15), p
- Subjects :
- Male
Drug research and development
Biochemistry
Hemoglobins
Clinical trials
0302 clinical medicine
Medicine and Health Sciences
Image Processing, Computer-Assisted
Photography
Prospective Studies
030212 general & internal medicine
Prospective cohort study
Skin
Aged, 80 and over
education.field_of_study
Multidisciplinary
030503 health policy & services
Anemia
Hematology
Middle Aged
Cardiology
Engineering and Technology
Medicine
Female
Smartphone
Anatomy
0305 other medical science
Conjunctiva
Phase II clinical investigation
Algorithms
Research Article
Adult
Computer and Information Sciences
medicine.medical_specialty
Imaging Techniques
Science
Population
Equipment
Image Analysis
Digital Imaging
Sensitivity and Specificity
Teaching hospital
Young Adult
03 medical and health sciences
Ocular System
Region of interest
Internal medicine
medicine
Humans
Hemoglobin
Low hemoglobin
education
Aged
Communication Equipment
Pharmacology
business.industry
Biology and Life Sciences
Proteins
Reproducibility of Results
Stepwise regression
medicine.disease
Research and analysis methods
Clinical medicine
Eyes
Cell Phones
business
Head
Subjects
Details
- Language :
- English
- ISSN :
- 19326203
- Volume :
- 16
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- PLoS ONE
- Accession number :
- edsair.doi.dedup.....c0aed0f81d336e8911b4a7d9a46f6a2b