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Potential crosstalk of oxidative stress and immune response in poultry through phytochemicals — A review
- Source :
- Asian-Australasian Journal of Animal Sciences, Vol 32, Iss 3, Pp 309-319 (2019), Asian-Australasian Journal of Animal Sciences
- Publication Year :
- 2019
- Publisher :
- Asian Australasian Association of Animal Production Societies, 2019.
-
Abstract
- Phytochemicals which exist in various plants and fungi are non-nutritive compounds that exert numerous beneficial bioactive actions for animals. In recent years following the restriction of antibiotics, phytochemicals have been regarded as a primal selection when dealing with the challenges during the producing process in the poultry industry. The selected fast-growing broiler breed was more fragile when confronting the stressors in their growing environments. The disruption of oxidative balance that impairs the production performance in birds may somehow be linked to the immune system since oxidative stress and inflammatory damage are multi-stage processes. This review firstly discusses the individual influence of oxidative stress and inflammation on the poultry industry. Next, studies related to the application of phytochemicals or botanical compounds with the significance of their antioxidant and immunomodulatory abilities are reviewed. Furthermore, we bring up nuclear factor (erythroid-derived 2)-like 2 (Nrf2) and nuclear factor kappa B (NF-κB) for they are respectively the key transcription factors involved in oxidative stress and inflammation for elucidating the underlying signal transduction pathways. Finally, by the discussion about several reports using phytochemicals to regulate these transcription factors leading to the improvement of oxidative status, heme oxygenase-1 gene is found crucial for Nrf2-mediated NF-κB inhibition.
- Subjects :
- Antioxidant
medicine.medical_treatment
Phytochemicals
lcsh:Animal biochemistry
Inflammation
Oxidative phosphorylation
Biology
medicine.disease_cause
Article
Poultry
Immune system
medicine
Immune Response
lcsh:QP501-801
Transcription factor
lcsh:SF1-1100
Review Paper
Cell biology
Oxidative Stress
Crosstalk (biology)
Animal Science and Zoology
lcsh:Animal culture
Signal transduction
medicine.symptom
Oxidative stress
Food Science
Subjects
Details
- ISSN :
- 19765517 and 10112367
- Volume :
- 32
- Database :
- OpenAIRE
- Journal :
- Asian-Australasian Journal of Animal Sciences
- Accession number :
- edsair.doi.dedup.....c10452716d53277c1b17a1942ef30f31