Back to Search
Start Over
Prevalence of ECGs Exceeding Thresholds for ST‐Segment–Elevation Myocardial Infarction in Apparently Healthy Individuals: The Role of Ethnicity
- Source :
- Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease, 9(13). WILEY, Journal of the American Heart Association, 9(13). Wiley-Blackwell, Journal of the American Heart Association, 9(13):e015477. Wiley, Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
- Publication Year :
- 2020
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2020.
-
Abstract
- Background Early prehospital recognition of critical conditions such as ST‐segment–elevation myocardial infarction (STEMI) has prognostic relevance. Current international electrocardiographic STEMI thresholds are predominantly based on individuals of Western European descent. However, because of ethnic electrocardiographic variability both in health and disease, there is a need to reevaluate diagnostic ST‐segment elevation thresholds for different populations. We hypothesized that fulfillment of ST‐segment elevation thresholds of STEMI criteria (STE‐ECGs) in apparently healthy individuals is ethnicity dependent. Methods and Results HELIUS (Healthy Life in an Urban Setting) is a multiethnic cohort study including 10 783 apparently healthy subjects of 6 different ethnicities (African Surinamese, Dutch, Ghanaian, Moroccan, South Asian Surinamese, and Turkish). Prevalence of STE‐ECGs across ethnicities, sexes, and age groups was assessed with respect to the 2 international STEMI thresholds: sex and age specific versus sex specific. Mean prevalence of STE‐ECGs was 2.8% to 3.4% (age/sex‐specific and sex‐specific thresholds, respectively), although with large ethnicity‐dependent variability. Prevalences in Western European Dutch were 2.3% to 3.0%, but excessively higher in young (45% STE‐ECGs. Conclusions The accuracy of diagnostic tests partly relies on background prevalence in healthy individuals. In apparently healthy subjects, there is a highly variable ethnicity‐dependent prevalence of ECGs with ST‐segment elevations exceeding STEMI thresholds. This has potential consequences for STEMI evaluations in individuals who are not of Western European descent, putatively resulting in adverse outcomes with both over‐ and underdiagnosis of STEMI.
- Subjects :
- Adult
Male
medicine.medical_specialty
Adolescent
Epidemiology
HELIUS study
Ethnic group
Action Potentials
Risk Assessment
STEMI
Electrocardiography
Young Adult
Heart Rate
Predictive Value of Tests
Internal medicine
Prevalence
medicine
Coronary Heart Disease
Humans
ST segment
Women
cardiovascular diseases
Myocardial infarction
Critical condition
Original Research
Aged
Netherlands
Electrocardiology (ECG)
Missed Diagnosis
population study
ECG
business.industry
Elevation
Reproducibility of Results
Health Status Disparities
Middle Aged
medicine.disease
Race Factors
Heart Disease Risk Factors
Healthy individuals
Cardiology
ST Elevation Myocardial Infarction
ethnicity
Population study
Female
Cardiology and Cardiovascular Medicine
business
Acute Coronary Syndromes
Subjects
Details
- ISSN :
- 20479980 and 00392499
- Volume :
- 9
- Database :
- OpenAIRE
- Journal :
- Journal of the American Heart Association
- Accession number :
- edsair.doi.dedup.....c1312be359c7ebcfc98f7dc3738fd33c