Back to Search
Start Over
TASK-1, TASK-2, TASK-3 and TRAAK immunoreactivities in the rat carotid body
- Source :
- Brain Research. 950:304-307
- Publication Year :
- 2002
- Publisher :
- Elsevier BV, 2002.
-
Abstract
- In the present study, we investigated the immunohistochemical localization of two-pore K + -channels TASK-1, TASK-2, TASK-3 and TRAAK in the rat carotid body. Type I cells were positive for TASK-1, TASK-2, TASK-3 and TRAAK. Intrinsic nerve cell bodies were also strongly positive for TASK-1, TASK-2 and TRAAK, but negative for TASK-3. In addition, some type II cells, Schwann cells in the nerve bundles and fibroblast between type I cell clusters were also immunostained for TASK-1. Smooth muscle cells of the carotid body artery were intensely positive for TASK-3. Our results indicate that TASK-1 immunoreactivity was ubiquitously distributed in many cell types and immunoreactivities for TASK-2, TASK-3 and TRAAK were cell type specific distribution patterns in the rat carotid body.
- Subjects :
- Male
Cell type
Pathology
medicine.medical_specialty
Potassium Channels
Chemoreceptor
Cell type specific
Cell
Nerve Tissue Proteins
Biology
behavioral disciplines and activities
Potassium Channels, Tandem Pore Domain
medicine
Animals
Rats, Wistar
Fibroblast
Molecular Biology
Carotid Body
General Neuroscience
Immunohistochemistry
Rats
medicine.anatomical_structure
Female
Carotid body
Neurology (clinical)
psychological phenomena and processes
Developmental Biology
Artery
Subjects
Details
- ISSN :
- 00068993
- Volume :
- 950
- Database :
- OpenAIRE
- Journal :
- Brain Research
- Accession number :
- edsair.doi.dedup.....c1c89231fb38a5a98f9cb784fcf40285