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Non-islet Cell Tumor-induced Hypoinsulinemic Hypoglycemia in the Setting of Metastatic Desmoplastic Round Cell Tumor
- Source :
- Cureus
- Publication Year :
- 2019
- Publisher :
- Cureus, Inc., 2019.
-
Abstract
- A 24-year-old male with metastatic desmoplastic round cell tumor was admitted for fatigue and weakness after chemotherapy. The patient was found to be hypotensive, pancytopenic, and bacteremic. Early treatment with intravenous antibiotics and fluids was efficacious. The hospital course was complicated by recurrent hypoglycemia that was refractory to the standard hypoglycemia protocol. Initial workup revealed low serum insulin and normal C-peptide. Further evaluation revealed elevated IGF-II levels consistent with non-islet cell tumor-induced hypoglycemia. Euglycemia was subsequently achieved with aggressive and continuous infusion of intravenous 10% dextrose.
- Subjects :
- medicine.medical_specialty
Weakness
endocrine system diseases
medicine.medical_treatment
Recurrent hypoglycemia
desmoplastic round cell tumor
Cell
Hypoglycemia
paraneoplastic syndrome
Gastroenterology
Refractory
Internal medicine
Internal Medicine
medicine
non-islet cell tumor induced hypoglycemia
Chemotherapy
geography
geography.geographical_feature_category
business.industry
General Engineering
nutritional and metabolic diseases
medicine.disease
Islet
tumor induced hypoglycemia
medicine.anatomical_structure
Medical Education
Oncology
Round cell tumor
medicine.symptom
business
Subjects
Details
- ISSN :
- 21688184
- Database :
- OpenAIRE
- Journal :
- Cureus
- Accession number :
- edsair.doi.dedup.....c24ef2dc200522f22b3b8aab0e2fc693