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Identification of a hidden outbreak due to the spread of a VIM-3-producing, extensive drug-resistant Pseudomonas aeruginosa (XDRPA) clone at a regional hospital in Taiwan
- Source :
- Epidemiol Infect
- Publication Year :
- 2012
- Publisher :
- Cambridge University Press, 2012.
-
Abstract
- SUMMARYA review of the annual prevalence of Pseudomonas aeruginosa at a regional hospital in Taiwan revealed a significant increase in the incidence of extensive drug-resistant P. aeruginosa (XDRPA) from 2·1% in 2003 to 5·8% in 2007. The first XDRPA isolate was recovered in 2001 from the emergency ward. The widespread dissemination of XDRPA isolates to more than 10 other wards was discovered the following year. Six pulsotypes of 67 XDRPA isolates from 2006 onwards were identified and 91% were a single strain, suggesting the existence of a hidden outbreak. Prior to the recognition of the outbreak, the majority of cases were not considered to be healthcare-associated infections until molecular evidence was provided. A cohort measure was launched by the infection control practitioners that effectively controlled the outbreak. Patients with XDRPA were mostly referred from neighbouring long-term care facilities, which may have been the reservoir of the XDRPA clone.
- Subjects :
- medicine.medical_specialty
Time Factors
Epidemiology
Clone (cell biology)
Short Report
Taiwan
Drug resistance
Microbial Sensitivity Tests
medicine.disease_cause
Polymerase Chain Reaction
Microbiology
Disease Outbreaks
Disk Diffusion Antimicrobial Tests
Internal medicine
Drug Resistance, Multiple, Bacterial
medicine
Prevalence
Humans
Pseudomonas Infections
Hospitals, Teaching
Retrospective Studies
Cross Infection
Pseudomonas aeruginosa
business.industry
Incidence (epidemiology)
Outbreak
Anti-Bacterial Agents
Electrophoresis, Gel, Pulsed-Field
Regional hospital
Infectious Diseases
Cohort
business
Infection Control Practitioners
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Epidemiol Infect
- Accession number :
- edsair.doi.dedup.....c2d090de6097682da29fb266f459f959