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Cardiooncology—dealing with modern drug treatment, long-term complications, and cancer survivorship
- Source :
- Clinical & Experimental Metastasis
- Publication Year :
- 2021
- Publisher :
- Springer Netherlands, 2021.
-
Abstract
- Modern treatment strategies have improved prognosis and survival of patients with malignant diseases. The key components of tumor treatment are conventional chemotherapy, radiotherapy, targeted therapies, and immunotherapy. Cardiovascular side-effects may occur in the early phase of tumor therapy or even decades later. Therefore, knowledge and awareness of acute and long-lasting cardiac side effects of anti-cancer therapies are essential. Cardiotoxicity impairs quality of life and overall survival. The new cardiologic subspecialty ‘cardio-oncology’ deals with the different cardiovascular problems arising from tumor treatment and the relationship between cancer and heart diseases. Early detection and treatment of cardiotoxicity is of crucial importance. A detailed cardiac assessment of patients prior to administration of cardiotoxic agents, during and after treatment should be performed in all patients. The current review focusses on acute and long-term cardiotoxic side effects of classical cytotoxic and selected modern drug treatments such as immune checkpoint inhibitors and discusses strategies for the diagnosis of treatment-related adverse cardiovascular effects in cancer patients.
- Subjects :
- Cancer Research
medicine.medical_specialty
Cancer survivorship
medicine.medical_treatment
Long-term complications
Antineoplastic Agents
Review
030204 cardiovascular system & hematology
Subspecialty
Cardiovascular System
03 medical and health sciences
0302 clinical medicine
Cancer Survivors
Surgical oncology
Internal medicine
Neoplasms
medicine
Chemotherapy
Humans
Intensive care medicine
Immune Checkpoint Inhibitors
Cardiotoxicity
Hematology
business.industry
Cancer
General Medicine
Immunotherapy
medicine.disease
Myocardial dysfunction
Radiation therapy
Cardio-oncology
Oncology
030220 oncology & carcinogenesis
business
Subjects
Details
- Language :
- English
- ISSN :
- 15737276 and 02620898
- Volume :
- 38
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Clinical & Experimental Metastasis
- Accession number :
- edsair.doi.dedup.....c2d317ec1737d6c0049735d0849909b8