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Additional file 1 of 1,5-Anhydroglucitol promotes pre-B acute lymphocytic leukemia progression by driving glycolysis and reactive oxygen species formation

Authors :
Zhu, Huasu
Ma, Huixian
Dong, Na
Wu, Min
Li, Dong
Liu, Linghong
Shi, Qing
Ju, Xiuli
Publication Year :
2023
Publisher :
figshare, 2023.

Abstract

Additional file 1: Supplementary data for some experiments. Fig. S1. Identification of 1,5-AG metabolite by liquid chromatography and mass spectrometry (LC-MS). Fig. S2. Effects of different concentrations of vitamin C on pre-B ALL cell viability (A) and apoptosis (B). 0.2 mM vitamin C was chosen as the intervention concentration. (C) Effects of 1,5-AG with 0.2 mM Vitamin C on cell cycle. Data are represented as mean ± SD; *p < 0.05, **p < 0.01, ***p < 0.001. Fig. S3. The infiltration of leukemia cells in BM (A) and spleen (B) for different groups on day 7 was analyzed by flow cytometry. Data were shown as mean ± SD (n = 5/group); ns (p ≥ 0.05); *p < 0.05; **p < 0.01. Table S1. Basic clinical characteristics of the patients.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....c325f552ff3300b55c002b4a702e69c2
Full Text :
https://doi.org/10.6084/m9.figshare.22602010