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G-CSF-induced aneuploidy does not affect CD34+ cells and does not require cell division
- Source :
- Blood, Blood, American Society of Hematology, 2010, 115 (4), pp.910-1. ⟨10.1182/blood-2009-10-250837⟩, Blood, 2010, 115 (4), pp.910-1. ⟨10.1182/blood-2009-10-250837⟩
- Publication Year :
- 2010
- Publisher :
- HAL CCSD, 2010.
-
Abstract
- To the editor: Lymphocytes from granulocyte colony-stimulating factor (G-CSF)–mobilized donors display epigenetic and genetic alterations similar to those observed in leukemia patients.[1][1] To further evaluate the scope and duration of G-CSF–induced genetic alterations, 24 healthy donors were
- Subjects :
- Male
Cell division
Cd34 cells
Aneuploidy
Antigens, CD34
030204 cardiovascular system & hematology
Biochemistry
MESH: Hematopoietic Stem Cells
0302 clinical medicine
Granulocyte Colony-Stimulating Factor
MESH: In Situ Hybridization, Fluorescence
In Situ Hybridization, Fluorescence
ComputingMilieux_MISCELLANEOUS
Leukemia
MESH: Middle Aged
Hematology
Middle Aged
Hematopoietic Stem Cell Mobilization
3. Good health
Granulocyte colony-stimulating factor
medicine.anatomical_structure
MESH: Young Adult
MESH: Cell Division
[SDV.IMM]Life Sciences [q-bio]/Immunology
Female
Cell Division
Adult
[SDV.IMM] Life Sciences [q-bio]/Immunology
Immunology
Biology
Granulocyte
MESH: Hematopoietic Stem Cell Mobilization
03 medical and health sciences
Young Adult
MESH: Leukemia
medicine
MESH: Aneuploidy
Humans
Epigenetics
MESH: Humans
Cell growth
MESH: Adult
Cell Biology
MESH: Antigens, CD34
medicine.disease
Hematopoietic Stem Cells
MESH: Male
MESH: Granulocyte Colony-Stimulating Factor
MESH: Female
030215 immunology
Subjects
Details
- Language :
- English
- ISSN :
- 00064971 and 15280020
- Database :
- OpenAIRE
- Journal :
- Blood, Blood, American Society of Hematology, 2010, 115 (4), pp.910-1. ⟨10.1182/blood-2009-10-250837⟩, Blood, 2010, 115 (4), pp.910-1. ⟨10.1182/blood-2009-10-250837⟩
- Accession number :
- edsair.doi.dedup.....c326ac2c6fc80fa6b27cbee16e3889e4
- Full Text :
- https://doi.org/10.1182/blood-2009-10-250837⟩