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Programmed ventricular stimulation in structural heart disease: Implications of patterns of ventricular arrhythmias induced to long-term outcomes
- Source :
- Indian heart journal.
- Publication Year :
- 2022
-
Abstract
- Currently available data gives some credence to utility of VT induction studies in patients with stable ischemic cardiomyopathy, there are some unresolved questions as to define sensitive threshold for low-risk and the prognostic relevance of ill sustained or non-specific tachycardia on induction study.We evaluated potential ability of VT inducibility to predict likelihood of SHD(Structural heart disease) patients for subsequent arrhythmic or adverse cardiac events.All consecutive patients with syncope/documented arrhythmia who had VT induction done were included and patients with VT storm, ACS,uncontrolled HF were excluded. We studied in 4 groups-monomorphic VT,sustained polymorphicVT,ill sustainedVT/VF and no VT/VF induced.The primary-endpoints were - Sudden death, all-cause mortality and secondary-endpoints were - MACE(AICD shock,death,HF, recurrence of VT).We screened 411 patients and included 169 within inducible(n=79) and non-inducible group(n=90).There were a higher number of patients with coronary artery disease, LV dysfunction, patients on amiodarone in inducible group and no difference in usage of beta-blockers. Recurrence of VT,composite of MACE was significantly higher in inducible group(p0.05).Mortality was not different in 3 groups compared with no VT/VF group.We found that monomorphic VT group had significantly higher MACE as compared to others and also predicted recurrence of VT and AICD shock and showed a trend towards significance for prediction of mortality. Inducible patients on AICD had mortality similar to non-inducible group.Induction of monomorphicVT/polymorphicVT with3extrastimuli is associated with a higher number of MACE events on follow up.Induction of monomorphicVT predicts recurrence of VT/ICD shock.
- Subjects :
- Cardiology and Cardiovascular Medicine
Subjects
Details
- ISSN :
- 22133763
- Database :
- OpenAIRE
- Journal :
- Indian heart journal
- Accession number :
- edsair.doi.dedup.....c3cdb9358bd5b88b8b0f62f0d9fd4df9