Back to Search Start Over

Pancreatic ductal adenocarcinoma with inferior vena cava invasion: a report of three resected cases

Authors :
Tadahiro Goto
Hirochika Toyama
Keitaro Sofue
Takuya Mizumoto
Takumi Fukumoto
Sadaki Asari
Masahiro Kido
Motofumi Tanaka
Yonson Ku
Tetsuo Ajiki
Sachio Terai
Source :
Surgical Case Reports, Surgical Case Reports, Vol 3, Iss 1, Pp 1-5 (2017)
Publication Year :
2017
Publisher :
Springer Science and Business Media LLC, 2017.

Abstract

Background Pancreatic ductal adenocarcinoma (PDAC) often infiltrates to the adjacent major vasculatures; however, direct invasion of PDAC to the inferior vena cava (IVC) is uncommon. Case presentation We report our experience with three cases of PDAC directly invading the IVC wall. All three patients underwent pancreatoduodenectomy along with wedge resection of the IVC wall without severe postoperative complications. Histopathological studies revealed tumor infiltration to the adventitia of the IVC. All patients achieved negative surgical margins. One patient was still alive 26 months after surgery without tumor recurrence. Two patients experienced recurrence; one patient experienced liver metastasis but was still alive and in a stable condition without further tumor progression 12 months after surgery. Another patient experienced multiple liver metastasis 10 months after surgery and died 26 months after surgery. Conclusions Pancreatoduodenectomy along with wedge resection of the IVC wall for patients with PDAC directly invading the adventitia of the IVC can be performed safely. Further accumulation of cases is needed to elucidate the prognostic impact of IVC invasion.

Details

ISSN :
21987793
Volume :
3
Database :
OpenAIRE
Journal :
Surgical Case Reports
Accession number :
edsair.doi.dedup.....c3cfaabd8aa49c83172ec405bd1a107c
Full Text :
https://doi.org/10.1186/s40792-017-0348-5