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Quality of evidence of the efficacy of therapeutic interventions on patient-important outcomes in Cochrane's systematic reviews’ abstracts: A survey
- Source :
- Alternative and Complementary Therapies, Alternative and Complementary Therapies, 2021, 76 (5), pp.403-408. ⟨10.1016/j.therap.2020.09.004⟩, Alternative and Complementary Therapies, Mary Ann Liebert, 2020, ⟨10.1016/j.therap.2020.09.004⟩, Alternative and Complementary Therapies, Mary Ann Liebert, 2021, 76 (5), pp.403-408. ⟨10.1016/j.therap.2020.09.004⟩
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- International audience; OBJECTIVE: The objective of this study was to evaluate the proportion of therapeutics that have proven their efficacy on patient-important outcomes with a high quality of evidence among Cochrane systematic reviews (SRs). METHODS: We surveyed a random sample of 400 SRs’ abstracts published between September 2012 and December 2015, which compared therapeutic interventions with at least a placebo or no intervention control. The primary endpoint was the proportion of SRs with a statistically significant efficacy on a patient-important outcome and with a high quality of evidence. RESULTS: Among the 400 abstracts surveyed, 32 (8%) found efficacy on a patient-important outcome with a high quality of evidence. Half of the 400 SRs (50.2%) evaluated a pharmacological intervention and 12% of these found efficacy of the intervention on a patient-important outcome with a reported high quality of evidence. CONCLUSION: Based on an analysis of 400 abstracts of SRs from the Cochrane Collaboration, we found that there is a low number of therapeutic interventions which have proven their efficacy on patient-important outcomes with a high quality of evidence.
- Subjects :
- Evidence-based medicine
medicine.medical_specialty
030309 nutrition & dietetics
education
Psychological intervention
Placebo
03 medical and health sciences
0302 clinical medicine
Intervention (counseling)
parasitic diseases
Clinical endpoint
Medicine
Pharmacology (medical)
GRADE approach
Intensive care medicine
0303 health sciences
Cochrane collaboration
business.industry
[SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences
030205 complementary & alternative medicine
3. Good health
Quality of evidence
Patient-important outcome
Systematic review
business
Subjects
Details
- ISSN :
- 00405957 and 10762809
- Volume :
- 76
- Database :
- OpenAIRE
- Journal :
- Therapies
- Accession number :
- edsair.doi.dedup.....c496123f449b3ed0cccb5ea7d0c28d07