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Antimicrobial effects of positively charged, conductive electrospun polymer fibers
- Source :
- Mater Sci Eng C Mater Biol Appl
- Publication Year :
- 2020
- Publisher :
- Elsevier BV, 2020.
-
Abstract
- In recent years, electrospun polymer fibers have gained attention for various antibacterial applications. In this work, the effect of positively charged polymer fiber mats as antibacterial gauze is studied using electrospun poly(caprolactone) and polyaniline nanofibers. Chloroxylenol, an established anti-microbial agent is used for the first time as a secondary dopant to polyaniline during the electrospinning process to make the surface of the polyaniline fiber positively charged. Both Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli are used to investigate the antibacterial activity of the positively charged and uncharged polymer surfaces. The results surprisingly show that the polyaniline surface can inhibit the growth of both bacteria even when chloroxylenol is used below its minimum inhibitory concentration. This study provides new insights allowing the better understanding of dopant-based, intrinsically conducting polymer surfaces for use as antibacterial fiber mats.
- Subjects :
- Staphylococcus aureus
Materials science
Polymers
Nanofibers
Bioengineering
02 engineering and technology
010402 general chemistry
01 natural sciences
Article
Biomaterials
chemistry.chemical_compound
Anti-Infective Agents
Polyaniline
Escherichia coli
medicine
Fiber
Chloroxylenol
Conductive polymer
Polyaniline nanofibers
021001 nanoscience & nanotechnology
Electrospinning
Anti-Bacterial Agents
0104 chemical sciences
chemistry
Chemical engineering
Mechanics of Materials
Nanofiber
0210 nano-technology
Antibacterial activity
medicine.drug
Subjects
Details
- ISSN :
- 09284931
- Volume :
- 116
- Database :
- OpenAIRE
- Journal :
- Materials Science and Engineering: C
- Accession number :
- edsair.doi.dedup.....c4aad4cd4c042b2fce07e214e65b29e2