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Thymus Polypeptide Preparation Tactivin Restores Learning and Memory in Thymectomied Rats

Authors :
V. Ya. Arion
O. V. Belova
A. V. Novoseletskaya
V. I. Sergienko
N. M. Kiseleva
I. V. Zimina
A. N. Inozemtsev
O. V. Bystrova
Source :
Bulletin of experimental biology and medicine. 159(5)
Publication Year :
2014

Abstract

We studied the effects of tactivin and splenic polypeptides on learning and memory of thymectomized animals. In 3-week rats, thymectomy blocked active avoidance conditioning. Injections of tactivin (0.5 mg/kg) during 1 month after surgery restored learning capacity; splenic polypeptides were ineffective.

Details

ISSN :
15738221
Volume :
159
Issue :
5
Database :
OpenAIRE
Journal :
Bulletin of experimental biology and medicine
Accession number :
edsair.doi.dedup.....c4cd31e5d542735f2061dd36bf407b9d