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Improvement on the Antioxidant Activity of Polysaccharides by Submerged Fermentation of Shiraia bambusicola GDMCC 60438 (Ascomycota)
- Source :
- International Journal of Medicinal Mushrooms. 22:605-614
- Publication Year :
- 2020
- Publisher :
- Begell House, 2020.
-
Abstract
- Shiraia bambusicola strain GDMCC 60438, originally isolated from eastern China, was applied for production of polysaccharides through submerged fermentation with glucose and potato extracts. Compared with a polysaccharide content of 3.94 ± 0.92% in natural Sh. bambusicola stroma, 9.12 ± 0.36 g intracellular polysaccharides (SIP) could be produced in 100 g freeze-dried Sh. bambusicola mycelium after an optimized fermentation. The SIP showed an 88.65 ± 2.26% hydroxyl radical scavenging activity (HRSA) at the concentration of 4 mg/mL. It was higher than the 31.48 ± 3.12% HRSA of Sh. bambusicola stroma polysaccharide (SSP). In the meantime, a 5 mg/mL SIP showed an equivalent 2,2'-Azino-bis (3-ethylbenzthiazoline-6-sulfonic) acid radical (ABTS+) scavenging activity to ascorbic acid at 0.025 mg/mL. Gel chromatography analysis showed that the SIP had distinct polysaccharide fractions compared with the SSP. Submerged fermentation showed a promising prospect on high production of Sh. bambusicola polysaccharides with improved antioxidant activities.
- Subjects :
- Antioxidant
Free Radicals
medicine.medical_treatment
Polysaccharide
Applied Microbiology and Biotechnology
Antioxidants
chemistry.chemical_compound
Ascomycota
Polysaccharides
Drug Discovery
medicine
Food science
Mycelium
Pharmacology
chemistry.chemical_classification
ABTS
biology
Chemistry
Bambusicola
Ascorbic acid
biology.organism_classification
Shiraia bambusicola
Culture Media
Fermentation
Subjects
Details
- ISSN :
- 15219437
- Volume :
- 22
- Database :
- OpenAIRE
- Journal :
- International Journal of Medicinal Mushrooms
- Accession number :
- edsair.doi.dedup.....c5dc3d3cc8821327cf2b33becd8e8661