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Outcomes of ablation in Wolff-Parkinson-White-syndrome: Data from the German Ablation Registry
- Source :
- International Journal of Cardiology. 323:106-112
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- Aims Catheter ablation is recommended for symptomatic WPW-syndrome. Commonly perceived low recurrence rates were challenged recently. We sought to identify patient strata at increased risk. Method Of 12,566 patients enrolled at 52 German Ablation Registry sites from 2007 to 2010, 789 were treated for WPW-syndrome. Patients were included for symptomatic palpitations and tachycardia documentation. Follow-up duration was one year. Overall complications were defined as serious, access-related, and ablation-related. We adjudicated WPW-recurrence for re-ablation during follow-up. Risk strata included: admission for repeat ablation at registry entry; accessory pathway localization; antiarrhythmic medical treatment before the ablation. Results WPW-syndrome patients were 42.8 ± 16.2 years on average; 39.9% were women. A majority of 95.9% was symptomatic; in 84.4%, a tachycardia was documented. Seventy-six (9.6%) patients presented for repeat procedures. Accessory pathways were located in the left atrium (71.4%), right atrium (21.1%), septum (4.4%), or coronary sinus diverticula (2.1%). Prior antiarrhythmic medication was used in 43.7% of patients. No serious events occurred. The overall complication rate was 2.5% (ablation related 1.2%, access-related 1.3%). Major determinants for complications were presentation for re-ablation as registry index procedure (6.9% vs 2.2%; p = 0.016) and septal pathway location (left 2.0% vs septal 9.1%, p = 0.014). The overall re-ablation rate was 9.7%. Usage of prior antiarrhythmic medication was associated with higher recurrence rates (12.2% vs. 7.6%; p = 0.035). Conclusions Patients at higher complication risk may be identified by repeat procedure and septal pathway location. Prior antiarrhythmic medication was associated with higher recurrence rates. Our findings may help improving peri-procedural patient management and information.
- Subjects :
- Male
Tachycardia
medicine.medical_specialty
medicine.medical_treatment
Catheter ablation
Accessory pathway
030204 cardiovascular system & hematology
03 medical and health sciences
0302 clinical medicine
medicine
Palpitations
Humans
Registries
030212 general & internal medicine
Coronary sinus
Medical treatment
business.industry
Ablation
Accessory Atrioventricular Bundle
Surgery
Catheter Ablation
Female
Wolff-Parkinson-White Syndrome
medicine.symptom
Cardiology and Cardiovascular Medicine
Complication
business
Subjects
Details
- ISSN :
- 01675273
- Volume :
- 323
- Database :
- OpenAIRE
- Journal :
- International Journal of Cardiology
- Accession number :
- edsair.doi.dedup.....c5de155b9d376c9e5a29d073b644c174