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Regulatory T Cells: Exosomes Deliver Tolerance
- Source :
- Immunity. (1):3-5
- Publisher :
- Elsevier Inc.
-
Abstract
- T regulatory (Treg) cells enforce peripheral tolerance through regulation of diverse immune responses in a context-dependent manner. Okoye et al show one way in which Treg cells suppress Th1 cell responses is through non-autonomous gene silencing mediated by microRNA-containing exosomes.
- Subjects :
- Cell
Immunology
Peripheral tolerance
hemic and immune systems
chemical and pharmacologic phenomena
Biology
Exosomes
Treg cell
T-Lymphocytes, Regulatory
Microvesicles
Article
Immune tolerance
Cell biology
MicroRNAs
medicine.anatomical_structure
Immune system
Infectious Diseases
microRNA
medicine
Immune Tolerance
Gene silencing
Immunology and Allergy
Humans
Gene Silencing
Subjects
Details
- Language :
- English
- ISSN :
- 10747613
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Immunity
- Accession number :
- edsair.doi.dedup.....c61b53284fefecb3103bcbc5bb4809d9
- Full Text :
- https://doi.org/10.1016/j.immuni.2014.07.001