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Attenuation and genetic characteristics of a Moroccan strain of Camel pox virus

Authors :
Zahra, Bamouh
Jihane, Hamdi
Zouhair, Elkarhat
Siham, Fellahi
Khalid, Omari Tadlaoui
Douglas M, Watts
Ouafaa, Fassi Fihri
Mehdi, Elharrak
Source :
Vaccine. 40:6471-6480
Publication Year :
2022
Publisher :
Elsevier BV, 2022.

Abstract

Camel pox (CML) is a widespread infectious viral disease of camels that causes huge economic losses to the camel industry. In this study, a local strain of Camel pox virus (CMLV) was attenuated by 175 serial passages in Vero cells and the residual pathogenicity and infectivity were tested in naïve camels at 120, 150 and 175 passage levels. Also, the safety and immunogenicity of the 175th passage were evaluated in camels using a dose of 10

Details

ISSN :
0264410X
Volume :
40
Database :
OpenAIRE
Journal :
Vaccine
Accession number :
edsair.doi.dedup.....c61f4e74b53ae59bbf7a62189d1de46f
Full Text :
https://doi.org/10.1016/j.vaccine.2022.09.033