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Responsiveness of the 36-item Short Form Health Survey and the Lupus Quality of Life questionnaire in SLE
- Source :
- Rheumatology. 54:940-949
- Publication Year :
- 2014
- Publisher :
- Oxford University Press (OUP), 2014.
-
Abstract
- OBJECTIVES This study aimed to estimate the responsiveness to change of a generic [the 36-item Short Form Health Survey (SF-36)] and a specific health-related quality of life questionnaire [the Lupus Quality if Life questionnaire (LupusQoL)] according to SLE patients' self-reported changes in health status. METHODS In a cohort of 185 SLE patients, quality of life (QoL) was measured three times at 3 month intervals by the LupusQoL and SF-36 questionnaires. Anchors for responsiveness were defined by patients' global assessment of disease impact according to changes in a visual analogue scale (VAS), a 7-point Likert scale and a 0-3 scale of five patient-reported symptoms. Mean change and s.d. in worsening and improving patients according to anchors were estimated using mixed models for repeated measures. Standardized response means (SRMs) were calculated in each group. RESULTS Patients [mean age 39.6 years (s.d. 10.5), mean Safety of Estrogen in Lupus Erythematosus National Assessment-SLEDAI score 2.6 (s.d. 3.5)] answered a total of 515 questionnaires. For the VAS and Likert global anchors, worsening patients showed a significant decrease in all LupusQoL domains except for burden to others, body image and fatigue and all SF-36 domains with low to moderate responsiveness. Improving patients had a significant increase in all LupusQoL domains except for intimate relationship and all SF-36 domains except for physical functioning and global health with low to moderate responsiveness. Regarding similar domains in the SF-36 and LupusQoL, SRMs were higher in LupusQoL domains in improving patients, while SF-36 domains had larger SRMs in worsening patients. CONCLUSION Both the SF-36 and LupusQoL were responsive to changes in QoL in SLE patients over a 3 month interval. LupusQoL seems to be more appropriate to measure improvements in QoL.
- Subjects :
- Adult
Male
medicine.medical_specialty
Psychometrics
Visual Analog Scale
SF-36
Visual analogue scale
Health Status
Cohort Studies
Cost of Illness
Rheumatology
Quality of life
Surveys and Questionnaires
Body Image
medicine
Humans
Lupus Erythematosus, Systemic
Pharmacology (medical)
Prospective Studies
skin and connective tissue diseases
Prospective cohort study
business.industry
Repeated measures design
Middle Aged
Health Surveys
Cohort
Disease Progression
Quality of Life
Physical therapy
Female
France
Self Report
business
Cohort study
Subjects
Details
- ISSN :
- 14620332 and 14620324
- Volume :
- 54
- Database :
- OpenAIRE
- Journal :
- Rheumatology
- Accession number :
- edsair.doi.dedup.....c633f6d0c4ca6d2f3eb3178f3ea4e0af