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Long-term exposure to background air pollution related to respiratory and allergic health in schoolchildren
- Source :
- Clinical and Experimental Allergy, Clinical and Experimental Allergy, Wiley, 2005, 35 (10), pp.1279-87. ⟨10.1111/j.1365-2222.2005.02336.x⟩, Clinical and Experimental Allergy, 2005, 35 (10), pp.1279-87. ⟨10.1111/j.1365-2222.2005.02336.x⟩
- Publication Year :
- 2005
- Publisher :
- HAL CCSD, 2005.
-
Abstract
- International audience; BACKGROUND: The impact of air pollution on asthma and allergies still remains a debate. OBJECTIVE: Our cross-sectional study was intended to analyse the associations between long-term exposure to background air pollution and atopic and respiratory outcomes in a large population-based sample of schoolchildren. METHODS: Six thousand six hundred and seventy-two children aged 9-11 years recruited from 108 randomly schools in six French cities underwent a clinical examination including a skin prick test (SPT) to common allergens, exercise-induced bronchial reactivity (EIB) and skin examination for flexural dermatitis. The prevalence of asthma, allergic rhinitis (AR) and atopic dermatitis was assessed by a standardized health questionnaire completed by the parents. Three-year-averaged concentrations of air pollutants (NO2, SO2, PM10 and O3) were calculated at children' schools using measurements of background monitoring stations. RESULTS: After adjusting for confounders, EIB, lifetime asthma and lifetime AR were found to be positively related to an increase in the exposure to SO2, PM10 and O3. The adjusted odds ratios (aOR) per increase of 5 microg/m3 of SO2 was 1.39 (95% confidence interval (CI)=1.15-1.66) for EIB and 1.19 (1.00-1.41) for lifetime asthma. The aOR for lifetime AR per increase of 10 microg/m3 of PM10 was 1.32 (CI=1.04-1.68). Moreover, SPT positivity was associated with O3 (aOR=1.34; CI=1.24-1.46). Associations with past year symptoms were consistent, even if not always statistically significant. Results persisted in long-term resident (current address for at least 8 years) children. However, no consistent positive association was found with NO2. CONCLUSIONS: A moderate increase in long-term exposure to background ambient air pollution was associated with an increased prevalence of respiratory and atopic indicators in children.
- Subjects :
- Hypersensitivity, Immediate
Male
Allergy
MESH: Asthma
Cross-sectional study
MESH: Air Pollutants
Atopy
0302 clinical medicine
MESH: Child
Prevalence
Sulfur Dioxide
Immunology and Allergy
030212 general & internal medicine
Child
Rhinitis
Vehicle Emissions
Air Pollutants
Schools
MESH: Rhinitis
Atopic dermatitis
3. Good health
MESH: Vehicle Emissions
Epidemiological Monitoring
MESH: Ozone
Female
France
Bronchial Hyperreactivity
MESH: Hypersensitivity, Immediate
MESH: Environmental Monitoring
Environmental Monitoring
MESH: Air Pollution
MESH: Schools
Nitrogen Dioxide
Immunology
MESH: Sulfur Dioxide
MESH: Nitrogen Dioxide
Dermatitis, Atopic
03 medical and health sciences
Ozone
MESH: Cross-Sectional Studies
MESH: Skin Tests
Air Pollution
Environmental health
MESH: Dermatitis, Atopic
medicine
Humans
MESH: Prevalence
Skin Tests
Asthma
MESH: Humans
business.industry
MESH: Bronchial Hyperreactivity
Odds ratio
medicine.disease
Confidence interval
MESH: Male
respiratory tract diseases
MESH: France
Cross-Sectional Studies
030228 respiratory system
El Niño
[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
business
MESH: Female
Subjects
Details
- Language :
- English
- ISSN :
- 09547894 and 13652222
- Database :
- OpenAIRE
- Journal :
- Clinical and Experimental Allergy, Clinical and Experimental Allergy, Wiley, 2005, 35 (10), pp.1279-87. ⟨10.1111/j.1365-2222.2005.02336.x⟩, Clinical and Experimental Allergy, 2005, 35 (10), pp.1279-87. ⟨10.1111/j.1365-2222.2005.02336.x⟩
- Accession number :
- edsair.doi.dedup.....c6af1c7bfb5504bb765640b0c29b7098