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The 308-nm excimer laser treatment does not increase the risk of skin cancer in patients with vitiligo: A population-based retrospective cohort study
- Source :
- Pigment cellmelanoma researchREFERENCES. 32(5)
- Publication Year :
- 2018
-
Abstract
- A 308-nm excimer laser (EL) has been widely used to treat patients with localized vitiligo. However, data are rare on the influence of EL treatment on the risks of skin cancer. To evaluate the skin cancer risks after long-term EL treatment, we performed a nationwide population-based retrospective cohort study using the Korean National Health Insurance Claims Database. A total of 5,052 patients with vitiligo were classified into three groups according to the EL treatment sessions between 2009 and 2016: no, 50-99, and 100 or more EL treatments after 2-year washout period (2007 and 2008). Using multivariable Cox proportional hazard models, we found that the risks of actinic keratosis, non-melanoma skin cancers, and melanoma did not significantly differ among the groups, respectively. In conclusion, EL treatment would not increase the risks of premalignant skin lesions and skin cancers in patients with vitiligo. Based on our results, EL is likely to be a safe treatment option for patients with localized vitiligo.
- Subjects :
- 0301 basic medicine
Male
medicine.medical_specialty
Skin Neoplasms
Population
Vitiligo
Dermatology
General Biochemistry, Genetics and Molecular Biology
03 medical and health sciences
0302 clinical medicine
308 nm excimer laser
medicine
Humans
In patient
education
Aged
Retrospective Studies
Aged, 80 and over
education.field_of_study
integumentary system
business.industry
Melanoma
Actinic keratosis
Retrospective cohort study
Middle Aged
medicine.disease
030104 developmental biology
Treatment Outcome
Oncology
030220 oncology & carcinogenesis
Case-Control Studies
Female
Lasers, Excimer
Skin cancer
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 1755148X
- Volume :
- 32
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Pigment cellmelanoma researchREFERENCES
- Accession number :
- edsair.doi.dedup.....c7178429a1e156078d4bb190994bce10