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N-(2-(1H-Indol-3-yl)ethyl)-2-(2-fluoro-[1,1′-biphenyl]-4-yl)propanamide
- Source :
- Molbank, Vol 2021, Iss M1177, p M1177 (2021)
- Publication Year :
- 2021
- Publisher :
- MDPI AG, 2021.
-
Abstract
- N-(2-(1H-Indol-3-yl)ethyl)-2-(2-fluoro-[1,1′-biphenyl]-4-yl)propanamide was prepared by a reaction between tryptamine and flurbiprofen, applying N,N’-dicyclohexylcarbodiimide, as a coupling agent. The obtained new amide has a fragment similar to Brequinar, a compound used in SARS-CoV-2 treatment trials. The newly synthesized compound was fully analyzed and characterized via 1H, 13C-NMR, UV, IR, and mass spectral data.
- Subjects :
- Tryptamine
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Flurbiprofen
Biochemistry
Medicinal chemistry
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Amide
medicine
lcsh:Inorganic chemistry
Physical and Theoretical Chemistry
Spectral data
030304 developmental biology
Biphenyl
0303 health sciences
SARS-CoV-2
Organic Chemistry
Propanamide
amide
lcsh:QD146-197
flurbiprofen
chemistry
030220 oncology & carcinogenesis
tryptamine
medicine.drug
Subjects
Details
- Language :
- English
- ISSN :
- 14228599
- Volume :
- 2021
- Database :
- OpenAIRE
- Journal :
- Molbank
- Accession number :
- edsair.doi.dedup.....c754d9a5e2befcb319b906b94c9e30d2