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N-(2-(1H-Indol-3-yl)ethyl)-2-(2-fluoro-[1,1′-biphenyl]-4-yl)propanamide

Authors :
Dimitar Bojilov
Stanimir Manolov
Iliyan Ivanov
Source :
Molbank, Vol 2021, Iss M1177, p M1177 (2021)
Publication Year :
2021
Publisher :
MDPI AG, 2021.

Abstract

N-(2-(1H-Indol-3-yl)ethyl)-2-(2-fluoro-[1,1′-biphenyl]-4-yl)propanamide was prepared by a reaction between tryptamine and flurbiprofen, applying N,N’-dicyclohexylcarbodiimide, as a coupling agent. The obtained new amide has a fragment similar to Brequinar, a compound used in SARS-CoV-2 treatment trials. The newly synthesized compound was fully analyzed and characterized via 1H, 13C-NMR, UV, IR, and mass spectral data.

Details

Language :
English
ISSN :
14228599
Volume :
2021
Database :
OpenAIRE
Journal :
Molbank
Accession number :
edsair.doi.dedup.....c754d9a5e2befcb319b906b94c9e30d2