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A Longitudinal Study on the Prevalence and Risk Factors for Depression and Anxiety, Quality of Life, and Clinical Outcomes in Incident Peritoneal Dialysis Patients
- Source :
- Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis. 39(1)
- Publication Year :
- 2017
-
Abstract
- Background Starting dialysis is an important life event. The prevalence and evolution of psychological symptoms at commencement of long-term dialysis is unclear. We examined the prevalence of and risk factors for depression and anxiety, and the quality of life (QOL) of incident peritoneal dialysis (PD) patients, and also the change of these parameters in the first year of PD in relation to clinical outcomes under the PD-first policy. Methods All patients commencing long-term PD from March 2011 to April 2015 were asked to complete the Hospital Anxiety and Depression Scale (HADS), World Health Organization Quality of Life-BREF and the Kidney Disease Quality of Life Instrument Short Form questionnaire. Patient demographics and the incidence of hospitalization, peritonitis, exit-site infection, and all-cause mortality were studied. The HADS was repeated after 9 – 12 months. Results A high depression score was present in 39.6% of 191 patients at commencement of PD and was more common in diabetes patients (odds ratio [OR] 2.03, 95% confidence interval [CI] 1.09 – 3.81). A high anxiety score was present in 23.6%, and the risk factors included younger age (OR 0.96 per year, 95% CI 0.94 – 0.99) and diabetes (OR 2.59, 95% CI 1.20 – 5.57). Both high depression and anxiety scores were associated with an inferior QOL, overall and across most QOL domains. Depression and anxiety symptoms did not change in the first year of PD and were not associated with short-term clinical outcomes. Conclusions High depression and anxiety scores were prevalent in incident PD patients where PD-first policy is adopted and were associated with inferior QOL. There was no improvement after 1 year of PD. The impact of strategic interventions targeting patient groups at risk such as those with diabetes or of younger age warrants further investigation.
- Subjects :
- Adult
Male
Longitudinal study
medicine.medical_specialty
medicine.medical_treatment
030232 urology & nephrology
Anxiety
Peritoneal dialysis
03 medical and health sciences
0302 clinical medicine
Quality of life (healthcare)
Risk Factors
Surveys and Questionnaires
medicine
Prevalence
Humans
030212 general & internal medicine
Longitudinal Studies
Dialysis
Depression (differential diagnoses)
Aged
business.industry
Depression
Life events
General Medicine
Middle Aged
Survival Analysis
Nephrology
Emergency medicine
Quality of Life
Hong Kong
Kidney Failure, Chronic
Female
medicine.symptom
business
Peritoneal Dialysis
Subjects
Details
- ISSN :
- 17184304
- Volume :
- 39
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis
- Accession number :
- edsair.doi.dedup.....c7b8fa62018382f93a679a65d75a5140